For example, in cardiac muscle cells, the concentration of K* in the ICF and ECF are typically about 135mM, and 4mM, respectively. [K*]ICF = 135mM, [K*]ECF = 4MM. Can you calculate a potential difference which results in the concentration of K+ ions between ICF and ECF

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The contractions of the heart are controlled by electrical phenomena, as are nerve impulses throughout the
body. The pulses of electricity that cause the heart to beat result from a remarkable combination of
electrochemistry and the properties of semipermeable membranes.
Cell walls are membranes with variable permeability with respect to number of physiologically important ions.
Especially Na+, K+ and Ca²+. The concentrations of these ions are different for the fluids inside the cells
(intracellular fluid, ICF) and outside the cells (extracellular fluid, ECF). Changes in the relative concentration of
the ions in the ECF and ICF lead to changes in the emf of the voltaic cell.
For example, in cardiac muscle cells, the concentration of K* in the ICF and ECF are typically about 135mM, and
4mM, respectively. [K*]₁cf = 135mM, [K*]µ£cf = 4mM.
Can you calculate a potential difference which results in the concentration of K+ ions between ICF and ECF
using the Nernst equation at the physiological temperature of 37°C in mV for moving K* from ECF to ICF?
Transcribed Image Text:The contractions of the heart are controlled by electrical phenomena, as are nerve impulses throughout the body. The pulses of electricity that cause the heart to beat result from a remarkable combination of electrochemistry and the properties of semipermeable membranes. Cell walls are membranes with variable permeability with respect to number of physiologically important ions. Especially Na+, K+ and Ca²+. The concentrations of these ions are different for the fluids inside the cells (intracellular fluid, ICF) and outside the cells (extracellular fluid, ECF). Changes in the relative concentration of the ions in the ECF and ICF lead to changes in the emf of the voltaic cell. For example, in cardiac muscle cells, the concentration of K* in the ICF and ECF are typically about 135mM, and 4mM, respectively. [K*]₁cf = 135mM, [K*]µ£cf = 4mM. Can you calculate a potential difference which results in the concentration of K+ ions between ICF and ECF using the Nernst equation at the physiological temperature of 37°C in mV for moving K* from ECF to ICF?
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