For each of the substrates below, identify whether: (A) the rate of substitution doesn't depend on nucleophile concentration and (B) the product distribution from substitution gives a 50/50 mix of enantiomers. If you answered "yes" for the first susbtrate, draw the intermediate that forms during a nucleophilic substitution reaction in the space below the table.

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For each of the substrates below, identify whether:

(A) the rate of substitution doesn't depend on nucleophile concentration and (B) the product distribution from substitution gives a 50/50 mix of enantiomers. If you answered "yes" for the first susbtrate, draw the intermediate that forms during a nucleophilic substitution reaction in the space below the table.

## Substrate Analysis: Questionnaire

This educational guide focuses on evaluating the truthfulness of both statements A and B regarding various chemical substrates. Review the chemical structure and select "yes" or "no" based on the given conditions.

### Substrates and Questionnaire:

1. **First Substrate:**
   - **Chemical Structure:** Contains a bromine atom (Br) along with a double-bonded carbon chain in a linear arrangement. The Br is depicted with a wedge, indicating stereochemistry.
   - **Question:** Are both A and B true?
     - ○ yes
     - ○ no

2. **Second Substrate:**
   - **Chemical Structure:** Similar linear carbon chain with a double bond, but with the bromine atom also depicted with stereochemistry indicated via a wedge.
   - **Question:** Are both A and B true?
     - ○ yes
     - ○ no

3. **Third Substrate:**
   - **Chemical Structure:** Features a chlorine atom (Cl) in a cyclic structure with branching alkyl groups. The Cl is depicted with a wedge.
   - **Question:** Are both A and B true?
     - ○ yes
     - ○ no

4. **Fourth Substrate:**
   - **Chemical Structure:** Shows an iodine atom (I) with multiple branching alkyl groups attached.
   - **Question:** Are both A and B true?
     - ○ yes
     - ○ no

This exercise is aimed at understanding stereochemistry and evaluating specific chemical substrates. Select your answer based on the criteria discussed in your study material.
Transcribed Image Text:## Substrate Analysis: Questionnaire This educational guide focuses on evaluating the truthfulness of both statements A and B regarding various chemical substrates. Review the chemical structure and select "yes" or "no" based on the given conditions. ### Substrates and Questionnaire: 1. **First Substrate:** - **Chemical Structure:** Contains a bromine atom (Br) along with a double-bonded carbon chain in a linear arrangement. The Br is depicted with a wedge, indicating stereochemistry. - **Question:** Are both A and B true? - ○ yes - ○ no 2. **Second Substrate:** - **Chemical Structure:** Similar linear carbon chain with a double bond, but with the bromine atom also depicted with stereochemistry indicated via a wedge. - **Question:** Are both A and B true? - ○ yes - ○ no 3. **Third Substrate:** - **Chemical Structure:** Features a chlorine atom (Cl) in a cyclic structure with branching alkyl groups. The Cl is depicted with a wedge. - **Question:** Are both A and B true? - ○ yes - ○ no 4. **Fourth Substrate:** - **Chemical Structure:** Shows an iodine atom (I) with multiple branching alkyl groups attached. - **Question:** Are both A and B true? - ○ yes - ○ no This exercise is aimed at understanding stereochemistry and evaluating specific chemical substrates. Select your answer based on the criteria discussed in your study material.
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