Following overnight (6 p.m. to 8 a.m.) fluid deprivation, the urine-to-serum osmolarity ratio in a patient who is exhibiting polyuria and polydipsia is 1:1. The ratio remains the same when a second specimen is tested at 10 a.m. ADH is then administered subcutaneously to the patient, and the fluid deprivation is continued until 2 p.m., when another specimen is tested. Based on the findings, what is the possible disease/disorder of the patient? Discuss the pathophysiology of the disease/disorder. Give two (2) possible laboratory tests that will be requested to confirm the diagnosis. Discuss the significance of requesting the laboratory tests.

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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Following overnight (6 p.m. to 8 a.m.) fluid deprivation, the urine-to-serum osmolarity ratio in a patient who is exhibiting polyuria and polydipsia is 1:1. The ratio remains the same when a second specimen is tested at 10 a.m. ADH is then administered subcutaneously to the patient, and the fluid deprivation is continued until 2 p.m., when another specimen is tested.

  1. Based on the findings, what is the possible disease/disorder of the patient?

  2. Discuss the pathophysiology of the disease/disorder.

  3. Give two (2) possible laboratory tests that will be requested to confirm the diagnosis. Discuss the significance of requesting the laboratory tests.

  4. What are the laboratory findings that will confirm the diagnosis? Give two (2) laboratory findings.

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