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- Write down the Similarities and dissimilarities of Urinary tract infection (UTI) management in man and woman? Or, Compare and contrast of UTI management in man and woman? Please explain at your own words.Consider a drug which is exogenous to the body. The drug is filtered, but not secreted, reabsorbed, or metabolised by the kidneys. The drug is constantly infused in a patient to maintain a plasma concentration of 2mg/L. 24 hour urine collection shows the drug being excreted at a rate of 400µg/min. What is this patient's GFR? 50ml/min 100ml/min 150ml/min 200ml/min 400ml/minHow does ANP control kidney function? Please include all outlined factors in explanation
- Should kidney dialysis centers be held to the same safety standards as other healthcare facilities?The renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations. For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion Explain how you determined this.Provide a strategy for one or two approaches to improve, the demand for a kidney transplant or expanding the supply of kidney transplants. What can be done to make it more likely that the waitlist will be shorter?
- BIUA A- |= ==而带 2) Complete this additional activity: Examine the below graph, which was published in a research paper. The graph depicts the % prevalence of Urinary Tract Infections (UTIS) in males versus females of different age groups. Answer these 2 questions related to the figure: 1. What is the main conclusion of the data presented in the graph below? 2. Why do you think this happens? 18.0% OMale OFemale (N-35,019) Figure taken from Shengsheng Yu, Alex Z. Fu, Ying Qlu, Samuel S. Engel, Ravi Shankar, Kimberly G. Brodovlcz, Swapnl lapathak, Larry Radican, "Disease burden of urinary tract infections among type 2 diabetes melitus patlents in the U.S Journal of Diabetes and its Complications, Volume 28, Issue 5,2014 14.0% .....l 201 18-24 18-24 25-34 55-64 65-74 75+ Male IN=38.132) 2.4% 2.74 4.34 6.5 10.1 16.2% Upload a PDF or a word file with your answers to Blackboard: Lab#11> Submit your completed UTI activity hereExplain the concept of a countercurrent multiplier system and how it works in the kidneys. What is the importance of this system to the function of the kidneys?which kidney is most preferred to use for a live donor transplantation?
- + 1. Summarize the role of the kidneys in each of the following functions: Adjusting blood volume (and so blood pressure) and the volume of interstitial fluid and lymph Regulating calcium ion levels Stimulating the production of red blood cells (erythropoiesis) Regulating blood pressure Regulating blood glucose levels Adjusting the pH of body fluids Regulating the blood Na* and K levels Regulating blood Cl levels Getting rid of wastes such as urea, ammonia, uric acid, creatinine, urobilin from breakdown of hemoglobin, foreign substances such as drugs and environmental toxinsMatch each clinical scenario to the most likely renal function. Each selection will be used ONCE. 1. Chronic Kidney Disease ONLY 2. Acute Kidney Injury ONLY 3. Acute on Chronic Kidney Disease (pre-existing CKD with concurrent AKI) 4. End-Stage Renal Disease A middle-aged patient with Type 1 DM has an Albumin-to- Creatinine urinary ratio (ACR) of 300 and a GFR of 47. Their serum creatinine is fairly close to their previous level. An otherwise healthy patient is admitted to the hospital for a traumatic injury resulting in massive blood loss. Their serum creatinine is very high compared to baseline. A patient whose baseline GFR is about 40 has received vancomycin antibiotic therapy for two weeks. Their serum creatinine is higher today than it was yesterday. A patient who has been diagnosed with CKD and albuminuria for several years has been told by their PCP that they need to start dialysis soon as they are experiencing significant fluid retention and hypertension despite taking loop…One model of the glomerular membrane is a microporous membrane in which right cylindrical pores penetrate all the way through the membrane. Assume that the pores have a length of 50 nm and a radius of 3.5 nm. The viscosity of plasma is 0.002 Pa s. The average hydrostatic pressure in the glomerulus is 60 mm Hg, hydrostatic pressure in Bowman's space is 20 mm Hg and the average oncotic pressure of glomerular capillary blood is 28 mm Hg. A. Calculate the flow through a single pore assuming laminar flow (use the Poiseuille flow equation) B. How many pores would there have to be to produce a normal GFR? C. If the total aggregate area of the kidneys for filtration is 1.5 m2, what is the density of the pores (number of pores per unit area)? D. What fraction of the area is present as pores?
