Following is a synthesis for toremifene, a nonsteroidal estrogen antagonist whose struc- ture is closely related to that of tamoxifen. 1. THP-O -Br, Mg 1. E:ONA 2. BICH,CH,OBn 2. H,O, HCI BnO A B 0-THP 0-THP HO Ho+ ОН OH BnO НО C D Cl. NMeg HCI F Toremifene

Q: Draw the products of attached reaction and indicate stereochemistry aroundstereogenic centers.

A: Given: To draw the product and indicate the stereochemistry of the reaction,

Q: What reagents are needed to carry out the conversion shown? HO i ㄷ O HOCH₂CH₂OH, H₂SO4; CH3CH2AICI3…

A:

Q: Draw the six products (including stereoisomers) formed when A is treated with NBS + hv. A NBS hv

A: Alkenes on reaction with NBS in the presence of light undergo bromination at allylic position.  Free…

Q: Fill in the missing products for each of the following reactions. All non-specified boxes with…

A: A)Glucose: H | H - C - H | H - C - H | OH Fructose: H | H - C = O | OH Galactose: H | H - C…

Q: Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting…

A:

Q: (c) ECH H₂ Pd/C (d) CH₂C=CCH₂CH3 + D₂ Draw the product of reaction (c). Incorrect Lindlar catalyst…

A: Alkynes can undergo reduction to form either alkenes or alkanes, depending on the specific reagents…

Q: Draw a stepwise mechanism for the biological conversion of linalyldiphosphate to limonene.

A: The mechanism is as follows: 1) The C-OPP undergoes heterolytic cleavage and that produce a stable…

Q: Cyclopentylnitrile is reduced with LİAIH4 and the resulting product reacts with…

A: Structure of Cyclopentylnitrile is as follows:-         LiAlH4 is Lithium Aluminium Hydride and it…

Q: Suzuki coupling of aryl iodide A and vinylborane B affords compound C,which is converted to D in the…

A: An organic reaction is considered as the Suzuki reaction in which a cross-coupling takes place where…

Q: 2) Complete the following: Stereochemistry and regiochemistry may be important. (10 pts) a) MeO₂C b)…

A: a) Reductive aminationb) Friedel-Crafts acylationc) Acetoacetic ester synthesis d) Benzylic…

Q: с. [1] Cl2 [2] NaNH2 (2 equiv) d. [1] R,BH [2] Н,0. Но- HC=C- + е. D20 f. H20 H,SO4

A: C.  Alkene reacts with chlorine to form a dichloro compound. The reaction follows an electrophilic…

Q: Draw the major product for each reaction showing the stereochemical outcome (syn or anti). Identify…

A: (c)

Q: The following reaction would yield: CH2CH3 CH₂OH H3C H3C An optically inactive product (racemic…

A: Alkyl halides give a solvolysis reaction with ethanol to form an ether.

Q: а) 1) CH3CH,MgBr 2) H20 b) 1) NaCN 2) H2O

A:

Q: Draw the mechanism for the formation of the epoxide of cyclopentene with first Br2/H2O followed by…

A: We have to predict the mechanism for the formation of epoxide of cyclopentene.

Q: draw the major product of the following reaction, and then the arrow-pushing mechanisnm H* CH;OH

A: In this question we have to do arrow pushing-mechanism epoxide ring opening. under Acidic condition,…