Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting an enzyme called HMG-CoA reductase. In one synthesis of atorvastatin that produces the desired single enantiomer of the final product, the following reagents are used. Draw the structure of synthetic intermediate A. ČI H3C- NaCN DMSO Но. Pyridine • Use the wedge/hash bond tools to indicate stereochemistry where it exists. Should you want to restart the exercise, the drop-down menu labeled == starting points == can be used to redraw the starting molecule on the sketcher. opy aste H3C CH3 CHHS HO. Previous Next CH3
Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting an enzyme called HMG-CoA reductase. In one synthesis of atorvastatin that produces the desired single enantiomer of the final product, the following reagents are used. Draw the structure of synthetic intermediate A. ČI H3C- NaCN DMSO Но. Pyridine • Use the wedge/hash bond tools to indicate stereochemistry where it exists. Should you want to restart the exercise, the drop-down menu labeled == starting points == can be used to redraw the starting molecule on the sketcher. opy aste H3C CH3 CHHS HO. Previous Next CH3
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter10: Alcohols
Section: Chapter Questions
Problem 10.57P
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![Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting an enzyme called HMG-CoA reductase. In one
synthesis of atorvastatin that produces the desired single enantiomer of the final product, the following reagents are used.
Draw the structure of synthetic intermediate A.
to
H3C-
-CI
NaCN
A
B
HO,
DMSO
Pyridine
Use the wedge/hash bond tools to indicate stereochemistry where it exists.
Should you want to restart the exercise, the drop-down menu labeled
on the sketcher.
starting points
can be used to redraw the starting molecule
P
aste
ору
H3C,
„CH3
CHEH3
НО.
CH3
Previous
Next
:O](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff974794a-323f-49d8-a468-88626f82713f%2F1fc2a30f-5fc7-4ba6-a63a-ce4825e35726%2Fmrbg53u_processed.png&w=3840&q=75)
Transcribed Image Text:Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting an enzyme called HMG-CoA reductase. In one
synthesis of atorvastatin that produces the desired single enantiomer of the final product, the following reagents are used.
Draw the structure of synthetic intermediate A.
to
H3C-
-CI
NaCN
A
B
HO,
DMSO
Pyridine
Use the wedge/hash bond tools to indicate stereochemistry where it exists.
Should you want to restart the exercise, the drop-down menu labeled
on the sketcher.
starting points
can be used to redraw the starting molecule
P
aste
ору
H3C,
„CH3
CHEH3
НО.
CH3
Previous
Next
:O
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