Following are the characteristics of organoids, except: Organoids are in vitro 3D clusters of cells deriving exclusively from primary tissue or stem cells O Organoids are capable of self-renewal and self-organization. 2D monolayer cultures are much closer to the in vivo situation than the organoids Spatially restricted cell-fate decisions contribute to self-organization in organoids.
Following are the characteristics of organoids, except: Organoids are in vitro 3D clusters of cells deriving exclusively from primary tissue or stem cells O Organoids are capable of self-renewal and self-organization. 2D monolayer cultures are much closer to the in vivo situation than the organoids Spatially restricted cell-fate decisions contribute to self-organization in organoids.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Following are the characteristics of organoids, except:
Organoids are in vitro 3D clusters of cells deriving exclusively from primary
tissue or stem cells
Organoids are capable of self-renewal and self-organization.
2D monolayer cultures are much closer to the in vivo situation than the
organoids
Spatially restricted cell-fate decisions contribute to self-organization in
organoids.
Transcribed Image Text:These are the key features of induced pluripotent stem cells (IPSCS) except:
Differentiated human cells can be re-programmed to pluripotency after exposing
them to a cocktail of four transcription factors known to be important in
embryonic development
no ethical concerns
(IPSCS), can be induced to differentiate into cell types that show associated
pathology in patients with the disease
IPSCS can be made by culturing cells from the inner cell mass of blastocysts from
surplus human embryos obtained during in vitro fertilization (IVF) procedures.
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