feet, shown in the image attached. Her past medical history is significant for pernicious anemia and hypertension. Which of the following best explains the underlying mechanism responsible for the lesions shown? Answers A - E A Absence of melanocytes in the skin B Aggregation of melanosomes within the cytoplasm of melanocytes C Linear pattern of melanocyte proliferation D Normal melanocytes number with increased melanin pigment E Poor melanin formation in melanocytes O O O O Q Q
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- A 31-year-old man presented with slowly spreading hyperpigmented and crusted lesions with the largest measuring 3 cm x 4 cm. The lesion started from the right sole of the foot and spread diffusely through the left ankle. He did not have similar lesions in the past, and there is no significant history of any chronic illness in the past. Upon examining his skin biopsy samples, the histopathological examination results showed: a. Pseudoepitheliomatous epidermal hyperplasia with the presence of pigmented spores arranged singly and in chains with peripheral neutrophil infiltration.b. Ziehl- Neelson staning negativec. PAS positived. Pus and granules negativee. Presence of granulomas along with golden- brown, thick- walled, spherical bodies about 5 to 8 μm in size. Questions: What disease can you infer from the results that are shown? Why have you said so? The case presented can be mistaken for what skin cancer? Why? What treatment is best to be given? What protective measures can be done to…Fill in the blank: Nodes of Ranvier occur between adjacent _______________________.A man comes to the Walk In clinic complaining of a golf-ball sized mass near his left groin. Upon physical examination, the mass is palpable, and warm to the touch, with a 5 cm radius of cellulitis. As the physician palpates the mass, a thick, purulent substance leaks out. The physician promptly collects the pus and sends it to the lab for testing. The physician then sends the man home with directions to apply heat to the area 3-4 times per day and to wait to hear what the lab results are before discussing a treatment plan. Below are the preliminary laboratory results: The physician orders a lab technician to perform a Kirby Bauer disk diffusion assay and finds that the organism is resistant to the following antibiotics: 1) Penicillin, 2) Ampicillin, 3) Methicillin, and 4) Trimethoprim/Sulfamethoxazole. Based upon this recent revelation, what drug would you choose to treat the patient with?
- Explain each step with detail mechanism of initiation progression and invasion-metastasis of malignant melanomaOccurs with any skin injury, infection, or V [Choose ] inflammation pallor flushed Due to high bilirubin levels cyanosis erythema carotenemia Excess of dietary carotenoids bruising jaundice Blood flow decreases, oxygen levels in the [ Choose ] tissues decline; skin takes on a bluish color Question 9 Melanin is made from the amino acid (You must spell this correctly to get the answer correct) Question 8 Which degree(s) of burn destroys not only the dermis and epidermis, but also the nerve endings? Choose all correct answers. O Fourth degree burn O First degree burn O Second degree burn O Third degree burnWrite the name of disease associated with type 1, 2, 3 and 4 collagen.