Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a norn man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability of the zygote. Viable normal, or translocation carrier Viable, with Down syndrome Inviable

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down
syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In
cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The
translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21.
Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a normal
man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability of
the zygote.
Viable normal, or translocation carrier
Viable, with Down syndrome
Inviable
Transcribed Image Text:Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a normal man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability of the zygote. Viable normal, or translocation carrier Viable, with Down syndrome Inviable
Answer Bank
two normal copies of 14, one normal copy of 21
two normal copies of 21, one 21 to 14 translocation, one normal copy of 14
two normal copies of 21, one normal copy of 14
to 14 translocation, one normal copy of 21, two normal copies of 14
one
two normal copies of 14, two normal copies of 21
one 21 to 14 translocation, one normal copy of 21, one normal copy of 14
Transcribed Image Text:Answer Bank two normal copies of 14, one normal copy of 21 two normal copies of 21, one 21 to 14 translocation, one normal copy of 14 two normal copies of 21, one normal copy of 14 to 14 translocation, one normal copy of 21, two normal copies of 14 one two normal copies of 14, two normal copies of 21 one 21 to 14 translocation, one normal copy of 21, one normal copy of 14
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