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F. F 5. Nirmatrelvir, known commercially as Paxlovid®, is the current antiviral treatment for COVID-19. F a. Circle the chiral centers present b. Indicate the maximum number of stereoisomers possible. NH HN H

F. F 5. Nirmatrelvir, known commercially as Paxlovid®, is the current antiviral treatment for COVID-19. F a. Circle the chiral centers present b. Indicate the maximum number of stereoisomers possible. NH HN H

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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5. **Nirmatrelvir**, known commercially as Paxlovid®, is the current antiviral treatment for COVID-19. a. Circle the chiral centers present. b. Indicate the maximum number of stereoisomers possible. **Diagram Explanation:** The diagram shows the molecular structure of Nirmatrelvir, which includes several distinctive features: - **Functional Groups and Atoms:** - Amide group (NHCO). - Nitrile group (CN). - Several fluorine atoms attached to a carbon atom. - **Chiral Centers:** - The molecule contains multiple carbon atoms connected to four different groups, which are potential chiral centers. These are typically marked with solid wedges in certain diagrams indicating stereochemistry. - **Structural Layout:** - The structure includes a bicyclic ring system on one side. - Various substituents such as NH and OH groups, which are significant for hydrogen bonding and molecular interaction. When addressing part (a), each chiral center in the structure should be identified by recognizing carbon atoms attached to four distinct groups. For part (b), the theoretical maximum number of stereoisomers is calculated using the formula 2^n, where n is the number of chiral centers identified.
Transcribed Image Text:5. **Nirmatrelvir**, known commercially as Paxlovid®, is the current antiviral treatment for COVID-19. a. Circle the chiral centers present. b. Indicate the maximum number of stereoisomers possible. **Diagram Explanation:** The diagram shows the molecular structure of Nirmatrelvir, which includes several distinctive features: - **Functional Groups and Atoms:** - Amide group (NHCO). - Nitrile group (CN). - Several fluorine atoms attached to a carbon atom. - **Chiral Centers:** - The molecule contains multiple carbon atoms connected to four different groups, which are potential chiral centers. These are typically marked with solid wedges in certain diagrams indicating stereochemistry. - **Structural Layout:** - The structure includes a bicyclic ring system on one side. - Various substituents such as NH and OH groups, which are significant for hydrogen bonding and molecular interaction. When addressing part (a), each chiral center in the structure should be identified by recognizing carbon atoms attached to four distinct groups. For part (b), the theoretical maximum number of stereoisomers is calculated using the formula 2^n, where n is the number of chiral centers identified.
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