Answered: Explain what pore-forming toxins are.…

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Explain what pore-forming toxins are. Give an example of one and why this is medically important.

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter4: Basic Immunology And Immunohematology

Section4.2: Infectious Mononucleosis Tests

Problem 2RQ

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Concept explainers

Reproductive system infection

The biological process through which parents produce new children is called reproduction. A reproductive system is a group of internal and external organs that collaborate to allow males and females to reproduce. Many experts believe that the reproductive system is one of the most important systems in the body due to its crucial function in the survival of the species. Among the body's basic systems, the reproductive tract is the one that differs the most between sexes, and it is also the only one that does not operate until puberty.

Question

Explain what pore-forming toxins are. Give an example of one and why this is medically
important.

Expert Solution

Step 1

Toxins are a metabolic product of the organism that damages the host. It can induce disease in absence of the organism that produced them.

There are a few important points about pore-forming toxins :

These toxins exert into the membrane of cells and form non-regulated forms.
It allows water, ions, and small molecules to enter and exit into it and causes the death of the cell.
Streptococcus pneumonia-producing pore-forming toxin.

The mode of action involved by pore-forming toxins are :

Receptor recognition
Activation by proteases
Aggregation into the oligomeric structures
Insertion into the membrane to form ionic forms.

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