Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Explain what pore-forming toxins are. Give an example of one and why this is medically
important.
Expert Solution
Step 1
Toxins are a metabolic product of the organism that damages the host. It can induce disease in absence of the organism that produced them.
There are a few important points about pore-forming toxins :
- These toxins exert into the membrane of cells and form non-regulated forms.
- It allows water, ions, and small molecules to enter and exit into it and causes the death of the cell.
- Streptococcus pneumonia-producing pore-forming toxin.
The mode of action involved by pore-forming toxins are :
- Receptor recognition
- Activation by proteases
- Aggregation into the oligomeric structures
- Insertion into the membrane to form ionic forms.
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