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explain how/why diuretics that block ADH secretion would work to reduce blood pressure (ie, what ASPECT of blood pressure is affected, and how is it affected)
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- Diuretics can be prescribed to combat high blood pressure. Thiazide is one of the most common. Describeits mechanism of action (they physiology of what the drug does) and how it combats high blood pressure. The action of the diuretic Thiazide can also cause the activation of the renin-angiotensin system. Explain this system (starting with renin) and whyit would be counterproductive to the reason you prescribed Thiazide for a patient. i only need answer for the question 2 Please!Indicate which of the following is (are) being described: angiotensisn II, aldosterone and/or ADH increases blood pressure by direct vasoconstriction (2 answers) stimulates insertion of aquaporins into the collecting duct (1) increases the secretion of the other two (1) acts on the principal cells of the nephron (2 answers) increases Na+ reabsorption by the kidney (1) has its production directly blocked by ACE inhibitors (1) increases water reabsorption by acting on kidney collecting duct (1)Which of the following mechanisms will increase vasopressin release from the pituitary gland (either directly or indirectly)? Select all that apply. Shrinking of osmoreceptor cells in the brain. Swelling of osmoreceptor cells in the brain. O A large drop in plasma volume (>15% reduction). A large increase in plasma volume (>15% increase). O A positive sodium balance. O A negative sodium balance.
- Diuretics cause sodium excretion. Sodium follows water. Therefore, diuretics lead to a reduction in volume (remember BP = heart rate x volume x blood vessel tone (SVR)). Since diuretics lower volume, they lower BP. When would diuretics be indicated? When would they be contraindicated?Diuretics can be prescribed to combat high blood pressure. Thiazide is one of the most common. Describeits mechanism of action (they physiology of what the drug does) and how it combats high blood pressure.Describe the renin-angiotensin-aldosterone system. State the function of this system. State how this system helps to control plasma Na+ concentrations and blood pressure.
- Which is TRUE of the RAAS pathway? angiotensin Il directly leads to vasoconstriction and stimulates aldosterone which promotes Na+ reabsorption at the cortical collecting duct ANP stimulates the RAAS pathway, while ADH/vasopressin inhibits the RAAS pathway increased plasma volume directly puts extra pressure on the afferent arteriole and indirectly increases pressure in the distal tubule, both of which lead to stimulation of renin release angiotensin Il promotes activation of the parasympathetic system which decreases GFR low plasma Na+ is sensed by the proximal tubule and triggers release of renin from JGA cellsActions of ACE inhibitors in hypertension and heart failure include all the following EXCEPT Decrease angiotensin ilves Decrease peripheral resistance Decrease bradykinin levels Decrease rease of aldosteroneAngiotensin IIa. causes vasoconstriction. d. increases the sensation of thirst.b. stimulates aldosterone secretion. e. All of these are correct.c. stimulates ADH secretion.
- Discuss how changes in blood pressure, osmolarity and volume affect the release of ADH/vasopressin.Describe the stimulus for the release of atrial natriuretic peptide (ANP) and its three actions.Two of the most common medications prescribed to patients suffering from hypertensionare Angiotensin-Converting Enzyme (ACE) inhibitors and diuretics. Make use of the relevant physiological mechanisms and explain the reasoning behind using these two separate drugs.
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