Ethylene glycol itself has relatively low toxicity. However, because of its properties, ethylene glycol undergoes fairly rapid biotransformation in the liver into a variety of toxic compounds. Alcohols undergo oxidation reactions to form aldehydes, which can be further oxidized to a carboxylic acid. Initially, ethylene glycol is oxidized to glycoaldehyde, which is oxidized to glycolic acid. 4. Show the oxidation of ethylene glycol to form glycoaldehyde (hint: only one of the alcohol groups is oxidized to an aldehyde).

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Ethylene glycol itself has relatively low toxicity. However, because of its properties, ethylene
glycol undergoes fairly rapid biotransformation in the liver into a variety of toxic compounds.
Alcohols undergo oxidation reactions to form aldehydes, which can be further oxidized to a
carboxylic acid. Initially, ethylene glycol is oxidized to glycoaldehyde, which is oxidized to
glycolic acid.
4. Show the oxidation of ethylene glycol to form glycoaldehyde (hint: only one of the
alcohol groups is oxidized to an aldehyde).
Transcribed Image Text:Ethylene glycol itself has relatively low toxicity. However, because of its properties, ethylene glycol undergoes fairly rapid biotransformation in the liver into a variety of toxic compounds. Alcohols undergo oxidation reactions to form aldehydes, which can be further oxidized to a carboxylic acid. Initially, ethylene glycol is oxidized to glycoaldehyde, which is oxidized to glycolic acid. 4. Show the oxidation of ethylene glycol to form glycoaldehyde (hint: only one of the alcohol groups is oxidized to an aldehyde).
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