Epoxide ring-opening using a Grignard reagent works well when at least one side of the epoxide is sterically unhindered. When the epoxide is substituted with groups that provide steric hindrance on both sides another type of reaction dominates. What type of reaction mechanism is occurring in the reaction shown? A E1 E2 C SN1 D SN2 E Addition

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Chapter1: Chemical Foundations
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Epoxide ring-opening using a Grignard
reagent works well when at least one
side of the epoxide is sterically
unhindered. When the epoxide is
substituted with groups that provide
steric hindrance on both sides another
type of reaction dominates.
What type of reaction mechanism is
occurring in the reaction shown?
A
E1
В
E2
C
SN1
D
SN2
E
Addition
OH
1) EtMgBr
2) H20
Transcribed Image Text:Epoxide ring-opening using a Grignard reagent works well when at least one side of the epoxide is sterically unhindered. When the epoxide is substituted with groups that provide steric hindrance on both sides another type of reaction dominates. What type of reaction mechanism is occurring in the reaction shown? A E1 В E2 C SN1 D SN2 E Addition OH 1) EtMgBr 2) H20
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