Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion catalysis.Acid‑base catalysisCovalent catalysisMetal ion catalysisAll Answer Banka Zn2+ cofactor may properlya covalent bond formsmay take part in interactionsa proton is transferredorient the substrate in the activebetween enzyme and substrateinvolving Fe2+between enzyme and substratesite through ionic interactionstwo part catalytic process (for example,catalyst retains its originaluses a nucleophiliclowers the energy or stabilizesthe chymotrypsin mechanism)form after reaction occursfunctional groupthe transition state or intermediatemay use amino acids such ascatalysts may participate inaspartate or lysine foroxidation-reduction reactionsprotonation or proton abstractionby changes in the oxidation state

Enzymes are biocatalysts which increase the rate of biochemical reactions. Substrate molecules bind…

Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion catalysis. Acid‑base catalysis Covalent catalysis Metal ion catalysis All

Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion catalysis. Acid‑base catalysis Covalent catalysis Metal ion catalysis All

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion catalysis.

Acid‑base catalysis

Covalent catalysis

Metal ion catalysis

All

Answer Bank
a Zn2+ cofactor may properly
a covalent bond forms
may take part in interactions
a proton is transferred
orient the substrate in the active
between enzyme and substrate
involving Fe2+
between enzyme and substrate
site through ionic interactions
two part catalytic process (for example,
catalyst retains its original
uses a nucleophilic
lowers the energy or stabilizes
the chymotrypsin mechanism)
form after reaction occurs
functional group
the transition state or intermediate
may use amino acids such as
catalysts may participate in
aspartate or lysine for
oxidation-reduction reactions
protonation or proton abstraction
by changes in the oxidation state

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