Q: Aminoacyl-tRNA synthetase joins amino acids to their cognate trna. Briefly discuss the two reactions…
A: Aminoacylation is mechanism of attachment of amino acid to tRNA. Aminoacyl-tRNA synthetase joins…
Q: Considering prokaryotes, what is the enzyme that links the tRNA molecules to its correct or cognate…
A: Ans- tRNA molecules serves as the link between the amino acid form of proteins and the genetic code…
Q: Three E. coli tRNA molecules with the anticodon sequences CGG, OGG , and UGG are charged with the…
A: During Protein synthesis or translation that occurs in ribosomes, messenger RNA code for an amino…
Q: A glycine residue is in position 210 of the tryptophan synthetase enzyme of wild-type E. coli. If…
A: Single base substitutions in which change in only one base pair occurs.
Q: What is the unique feature of ribozyme function? Give two examples.
A: Ribozymes are the ribonucleic acid molecules having the catalytic functions and are found rarely. A…
Q: What two reaction steps are required for the formation of an aminoacyl-tRNA?
A: In molecular biology, translation is the cycle wherein ribosomes in the cytoplasm or endoplasmic…
Q: How does the aminoacyl-tRNA synthetase that attaches the amino acid proline know which tRNA to…
A: tRNA is a small, well-characterized RNA molecule which plays a key role in protein biosynthesis.…
Q: What does tRNA stand for?
A: The central dogma is the theory explaining the process of gene expression that initiates from the…
Q: Which is the most deleterious type of amino acid substitution? Explain.
A: Amino acid substitutions are due to mutations in the the DNA that codes for the mRNA. These…
Q: How and when does formylmethionine become attached to the initiator tRNA in bacteria?
A: Bacterial cell is composed of three types of RNA: first type is mRNA, which codes for amino acid to…
Q: Which form of flavin adenine dinucleotide is the "reduced" form, FAD or FADH2? Explain
A: Flavin Adenine Dinucleotide: It is a redox active coenzyme associated with various proteins, which…
Q: Lactose permease, a protein of E. coli, is composed of a single polypeptide that is 417 amino acids…
A: Lactose permease Its belong to transmembrane protein family. The transport mechanism of lactose…
Q: Determine the codon sequence for the peptide sequence glycylserylcysteinylarginylalanine. How many…
A: Translation is the sequences process where the mRNA was translated into a polypeptide chain. Where…
Q: What are the properties of the wild type amino acid, Tyrosine at position 368? Hint: the amino…
A: Tyrosine is an aromatic protein.
Q: Which amino acid is carried by the tRNA with the anticodon 5'-UCA-3'? None-this is a stop codon. OI.…
A: The process of translation helps in formation of long chains of amino acids ie, polynucleotides. We…
Q: TRUE OR FALSE a) The structure of the purines and pyrimidines make them able to undergo keto-enol…
A: Purines and pyrimidines are nitrogen-containing aromatic compounds. They are the major components of…
Q: What makes the initiator tRNAmet so special? Does this have any impact on the amino acid sequence…
A: Protein synthesis is initiated by the start codon decoded by the tRNA. The anticodon triplet series…
Q: What are isoaccepting tRNAs?
A: Transfer ribonucleic acid (tRNA) is required during the translation process for the synthesis of…
Q: What naturally found amino acyl tRNA synthetase can be used to attach 2-aminobutyric acid to a tRNA?…
A: Higher living beings vary in their ability to synthesize the 20 common amino acids. Most bacteria…
Q: The anticodon loop of one of the tRNA Gly molecules from Escherichia coli is as follows: a)…
A: Anticodon is the sequence of nucleotides which is complementary to the codons. These are found on…
Q: The wobble pairing rule states that a 'U' in teh anticodon wobble position can pair with 'A' or 'G',…
A: Ribonucleic acid (RNA) is a nucleic acid found in both the nucleus and cytoplasm. It can be genetic…
Q: What are the sequences of all the possible tripeptides that contain the amino acids aspartic acid,…
A: The polypeptide chain is made up of amino acids which are joined by the polypeptide chain.
Q: When the amino acid sequences of insulin isolated from different organisms were determined,…
A: CENTRAL DOGMA- It is the process when DNA replicates itself means it will make copies of itself with…
Q: What is an anticodon and where is it located on the tRNA structure?
A: The anticodon is a distinctive three-nucleotide sequence present on transfer RNA (t RNA) molecules.…
Q: Based on the N-terminal amino acid sequence, what is the approximate half-life of the protein after…
A: Introduction- N-terminal methionine cleavage plays an important role in protein synthesis in…
Q: The gene encoding the E. coli enzyme enolase begins with the sequence ATGTCCAAAATCGTA. What is the…
A: The flow of genetic information from DNA to RNA and then RNA to protein is called central dogma. It…
Q: Considering prokaryotes, what is the term for the triplet of nucleotides that codes for an amino…
A: Asked : Term for the triplet of nucleotides that codes for an amino acid
Q: Why do bacteria use formylated methionine in the initiator tRNA, while eukaryotes do not?
A: Protein is a macronutrient that is vital for building muscle mass. It is normally found in creature…
Q: Human ribonucleotide reductase has two allosteric sites, the S site and the A site. What is the…
A: Human ribonucleotide reductase in a mammalian enzyme that is responsible for the conversion of RNA…
Q: There are different tRNAs for each amino acid. What is one major way to differentiate among the…
A: During the process of translation, the proteins are synthesized from the translational complex,…
Q: What are aminoacyl-tRNA synthetases?
A: Translation is the biosynthesis of a protein or a polypeptide sequence inside a living cell. In the…
Q: What are the amino acids carried by tRNAs if their anticodons are either 5'-CAU-3' and 3'-GUC-5'?
A: m RNA carries the codon and t RNA carries the anticodon. t RNA brings amino acid according to the…
Q: NA has an anticodon sequence 3′– GGU–5′. Identify the amino acid it is carrying?
A: Transfer RNA, often known as tRNA, is a tiny RNA molecule that takes role in the creation of…
Q: Why is it important for all tRNAs to have similar structures?
A: Transfer RNA (tRNA), certain molecules in the cell that carry amino acids to ribosomes. Here, they…
Q: E. coli oriC is rich in A · T base pairs. Why is this advantageous?
A: E.coli is a gram-negative bacteria that is found in the lower part of the intestine if warm blood…
E. coli has two tRNAs for methionine. What is the basis for the distinction between the two?
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- Shown in the following table are several amino acid substitutionsin the a and b chains of human hemoglobin. determine how many of them can occur as a result of a single nucleotide change.Considering prokaryotes, what is the enzyme that links the tRNA molecules to its correct or cognate amino acid?The gene encoding the E. coli enzyme enolase begins with the sequence ATGTCCAAAATCGTA. What is the sequence of the RNA transcript specified by this part of the gene? (5') (3¹')
- What makes the initiator tRNAmet so special? Does this have any impact on the amino acid sequence of all proteins?1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also charged methionine tRNAs with alanine? b)What would happen if an individual was homozygous for mutant alleles of the gene encoding the aminoacyl tRNA synthetase responsible for charging leucine tRNAs?A normal hemoglobin protein has a glutamic acid at position 6; in sickle-cell hemoglobin, this glutamic acid has been replaced by a valine. List all the possible mRNA codons that could be present for each type of hemoglobin. Can a single base change result in a change from Glu to Val in hemoglobin?
- In HbS, the human hemoglobin found in individuals with sickle-cell anemia, glutamic acid at position 6 in the beta chain is replaced by valine. Q.) Show that one of the glutamic acid codons can be converted to a valine codon by a single substitution mutation (i.e., by changing one letter in one codon).A gene contains 30% thymine. What is the percentage of pyrimidines present in this segment? Explain.Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human β-globin gene (Shown in Figure 17.11) into bacterial cells, hoping the cells will express it and synthesize functional β-globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does β-globin made by a eukaryotic cell. Explain why.
- For the anticodon sequences 5' IAA and 5' xm^3s^2UAA, considering the DNA sequences of the genes encoding the tRNAs(assuming both tRNAs exist even if that is not true), What is the sequence of the RNA-like strand of each tRNA gene that corresponds to the tRNA's anticodon? be sure to indicate polarities.Metenkephalin is a small peptide found in animal brains that has morphine-like properties. Give an mRNA sequence that could code for the synthesis of metenkephalin: Tyr-Gly-Gly-Phe-Met. Label your answer with 3′ and 5′ ends.Is the Aminoacyl tRNA synthetases in human cells specialized or non specialized? Explain.