During the decarboxylation of acetoacetate, what is the nucleophile and what is the electrophile? Is the formation of a schiff base simply a preparation step or is the formation of a schiff base formed also by nucleophile/electrophile interaction?
During the decarboxylation of acetoacetate, what is the nucleophile and what is the electrophile? Is the formation of a schiff base simply a preparation step or is the formation of a schiff base formed also by nucleophile/electrophile interaction?
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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During the decarboxylation of acetoacetate, what is the nucleophile and what is the electrophile? Is the formation of a schiff base simply a preparation step or is the formation of a schiff base formed also by nucleophile/electrophile interaction?
![CO₂
H+
Love 2 [onfron] I ow-t-ons
[CH₂]
ci
CH3-C-CH₂
CH3-C=
CH3-C-CH3
Acetoacetate
OH
-RNH₂
CH3-C-CH2
0:
Enolate
Acetoacetate decarboxylase
CO₂
H+
Figure 11-11
©2013 John Wiley & Sons, Inc. All rights reserved.
R
CH3-C=CH₂
in
Schiff base Electrophile
(imine)
RNH2
Acetone
-OH
H
CH3-C-CH3](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc061ccfc-c5c1-460b-8498-b5bc9ae72844%2Febd8ed2e-5b80-4268-8a37-3d9231703711%2Fusgsgg4_processed.png&w=3840&q=75)
Transcribed Image Text:CO₂
H+
Love 2 [onfron] I ow-t-ons
[CH₂]
ci
CH3-C-CH₂
CH3-C=
CH3-C-CH3
Acetoacetate
OH
-RNH₂
CH3-C-CH2
0:
Enolate
Acetoacetate decarboxylase
CO₂
H+
Figure 11-11
©2013 John Wiley & Sons, Inc. All rights reserved.
R
CH3-C=CH₂
in
Schiff base Electrophile
(imine)
RNH2
Acetone
-OH
H
CH3-C-CH3
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