During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important. Generally, these reactions are done by slowly adding the alkylating agent to the aromatic component. What is the advantage of mixing the ingredients in this order rather than slowly adding the aromatic component to the alkylating agent? + AICI, + AICI3 `CI add add slowly slowly CI

During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important. Generally, these reactions are done by slowly adding the alkylating agent to the aromatic component. What is the advantage of mixing the ingredients in this order rather than slowly adding the aromatic component to the alkylating agent? + AICI, + AICI3 `CI add add slowly slowly CI

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Add curved arrows to each step in the attached reaction sequence.
29 minutes, 42 seconds. Question Completion Status: A Moving to another question will save this response. Question 15 What is not an expected product of the following allylic substitution reaction? NBS, hv Br Br Compounds II and II Compound II only O Compound I only O Compound II only A Moving to another question will save this response O O C
help
Select the TWO most nucleophilic atoms in this molecule. HS
2. Draw the structures and explain why CH3CH₂O and CH3CO₂ are good nucleophiles but CH3SO3, water, and alcohols (R-OH) are poor nucleophiles. Propose a 'cutoff' for the amount of negative charge needed to be a good nucleophile. CH3CH₂O CH3CO₂ CH3SO3 H₂O CH₂OH
Drag the appropriate items to their respective bins. Nucleophiles OH BH3 H₂O +CH3 NH3 Electrophiles Br Reset Help
2. The intermediate in the following nucleophilic aromatic substitution reaction has at least 5 resonance structures. For this question, complete the following tasks: a. Show the mechanistic arrow(s) for the first step. b. Draw TWO of the many resonance structures of the intermediate, drawing out the -NO₂ groups in each. c. Draw the neutral product. يمهم NO₂ NO₂ HO and others neutral product
Alcohols are acidic in nature. Therefore, a strong base can abstract the acidic hydrogen atom of the alcohol in a process known as deprotonation. The alcohol forms an alkoxide ion by losing the proton attached to the oxygen atom of the hydroxyl ( -OH) group. The alkoxide formed can act as a base or a nucleophile depending on the substrate and reaction conditions. However, not all bases can abstract the acidic proton of alcohols and not all alcohols easily lose the proton. Deprotonation depends on the strength of the base and the acidity of the alcohol. Strong bases, such as NaNH2, can easily abstract a proton from almost all alcohols. Likewise, more acidic alcohols lose a proton more easily. Determine which of the following reactions would undergo deprotonation based on the strength of the base and the acidity of the alcohol. Check all that apply. ► View Available Hint(s) CH3CH,OH + NH3 →CH,CH,O-NH CH3 CH3 H3C-C-H+NH3 → H3 C-C-H OH O-NH CH3CH2OH + NaNH, → CH3CH,O-Na* + NH3 CHC12 Cl₂…
Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. CI + H₂N • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. OH • Do not include counter-ions, e.g., Na+, I¯, in your answer. • In cases where there is more than one answer, just draw one.
3. Draw all products for the following reactions. For your products, write whether the nucleophile added to the Re face or Si face of the starting material. a. HO b. 1) LIAIH 2) H™ 1) CH3CH2Li 2) H+ c) Determine whether the nucleophile added to the Re face or Si face of benzaldehyde.
a) Which student’s reaction (Danny or Claire) has provided a single elimination isomer? b) Draw all the elimination isomers obtained from both students’ reactions. c) Which of the dienes drawn (by you) in question 3b is the most stable? Circle that diene above.