Drug released (u mol A) 0.20 0.15 0.10 0.05 0.00 10 15 Time (h) 20 25 a) State the differential mass balance for diffusion through a membrane. b) State the boundary conditions. c) Explain why this system can be modeled at steady-state. d) Solve the differential equation and use the solution and Fick's Law to estimat diffusion coefficient.

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
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Drug released (u mol A)
0.20
0.15
0.10
0.05
0.00
0
10
Time (h)
15
20
25
a) State the differential mass balance for diffusion through a membrane.
b) State the boundary conditions.
c) Explain why this system can be modeled at steady-state.
d) Solve the differential equation and use the solution and Fick's Law to estimate the
diffusion coefficient.
Transcribed Image Text:Drug released (u mol A) 0.20 0.15 0.10 0.05 0.00 0 10 Time (h) 15 20 25 a) State the differential mass balance for diffusion through a membrane. b) State the boundary conditions. c) Explain why this system can be modeled at steady-state. d) Solve the differential equation and use the solution and Fick's Law to estimate the diffusion coefficient.
Impermeable.
barrier
Skin surface
Drug patch
Infected body tissue
(sink for drug)
-Drug reservoir
-Gel diffusion barrier
Transcribed Image Text:Impermeable. barrier Skin surface Drug patch Infected body tissue (sink for drug) -Drug reservoir -Gel diffusion barrier
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