Drug released (u mol A) 0.20 0.15 0.10 0.05 0.00 10 15 Time (h) 20 25 a) State the differential mass balance for diffusion through a membrane. b) State the boundary conditions. c) Explain why this system can be modeled at steady-state. d) Solve the differential equation and use the solution and Fick's Law to estimat diffusion coefficient.
Drug released (u mol A) 0.20 0.15 0.10 0.05 0.00 10 15 Time (h) 20 25 a) State the differential mass balance for diffusion through a membrane. b) State the boundary conditions. c) Explain why this system can be modeled at steady-state. d) Solve the differential equation and use the solution and Fick's Law to estimat diffusion coefficient.
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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Transcribed Image Text:Drug released (u mol A)
0.20
0.15
0.10
0.05
0.00
0
10
Time (h)
15
20
25
a) State the differential mass balance for diffusion through a membrane.
b) State the boundary conditions.
c) Explain why this system can be modeled at steady-state.
d) Solve the differential equation and use the solution and Fick's Law to estimate the
diffusion coefficient.

Transcribed Image Text:Impermeable.
barrier
Skin surface
Drug patch
Infected body tissue
(sink for drug)
-Drug reservoir
-Gel diffusion barrier
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