Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
Draw the predominant form of Gly-Gly when 2.0 moles of OH- is added.

Draw the predominant form of Gly-Gly when 2.0 moles of OH- is added.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
**Question: Draw the predominant form of Gly-Gly when 2.0 moles of OH⁻ is added.** In this exercise, you are asked to determine and draw the predominant form of the dipeptide Glycylglycine (Gly-Gly) upon addition of 2.0 moles of hydroxide ions (OH⁻). To solve this problem, one must consider the chemical structure of Gly-Gly and the effect of adding hydroxide ions. Hydroxide ions will likely deprotonate the amino and carboxyl groups in the peptide sequence. - **Gly-Gly Structure:** - Glycine (Gly) has the side chain -H. - In dipeptide form, two glycine molecules are linked by a peptide bond (CONH). The addition of OH⁻ typically results in the deprotonation of acidic protons: 1. Carboxyl (-COOH) group deprotonation leading to -COO⁻. 2. Amino (-NH₃⁺) deprotonation leading to -NH₂. Since 2.0 moles of OH⁻ are added, this sufficient quantity will fully deprotonate the available acidic protons in Gly-Gly. **Detailed Steps to Draw the Predominant Form:** 1. Begin with the Gly-Gly structure: ``` NH3⁺-CH2-CO-NH-CH2-COOH ``` 2. Identify the groups that can be deprotonated by OH⁻ action: - The NH3⁺ group can lose a proton to become NH2. - The COOH group can lose a proton to become COO⁻. 3. Upon addition of 2.0 moles of OH⁻, proton distribution will lead to: ``` NH2-CH2-CO-NH-CH2-COO⁻ ``` So, the predominant form should be represented as the structure provided above. This analysis helps understand the biochemical interactions in a basic environment where Gly-Gly is adjusted with a strong base like OH⁻.
Transcribed Image Text:**Question: Draw the predominant form of Gly-Gly when 2.0 moles of OH⁻ is added.** In this exercise, you are asked to determine and draw the predominant form of the dipeptide Glycylglycine (Gly-Gly) upon addition of 2.0 moles of hydroxide ions (OH⁻). To solve this problem, one must consider the chemical structure of Gly-Gly and the effect of adding hydroxide ions. Hydroxide ions will likely deprotonate the amino and carboxyl groups in the peptide sequence. - **Gly-Gly Structure:** - Glycine (Gly) has the side chain -H. - In dipeptide form, two glycine molecules are linked by a peptide bond (CONH). The addition of OH⁻ typically results in the deprotonation of acidic protons: 1. Carboxyl (-COOH) group deprotonation leading to -COO⁻. 2. Amino (-NH₃⁺) deprotonation leading to -NH₂. Since 2.0 moles of OH⁻ are added, this sufficient quantity will fully deprotonate the available acidic protons in Gly-Gly. **Detailed Steps to Draw the Predominant Form:** 1. Begin with the Gly-Gly structure: ``` NH3⁺-CH2-CO-NH-CH2-COOH ``` 2. Identify the groups that can be deprotonated by OH⁻ action: - The NH3⁺ group can lose a proton to become NH2. - The COOH group can lose a proton to become COO⁻. 3. Upon addition of 2.0 moles of OH⁻, proton distribution will lead to: ``` NH2-CH2-CO-NH-CH2-COO⁻ ``` So, the predominant form should be represented as the structure provided above. This analysis helps understand the biochemical interactions in a basic environment where Gly-Gly is adjusted with a strong base like OH⁻.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps with 3 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS