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Draw the missing organic structures in the following multistep synthesis. Show all structures at physiological pH (pH = 7.4). Ignore any inorganic byproducts formed. H₂ N + Select to Draw 00 Q BnOH H2SO4 H₂O OH- Select to Draw BOC-Ala DCC Select to Draw

Draw the missing organic structures in the following multistep synthesis. Show all structures at physiological pH (pH = 7.4). Ignore any inorganic byproducts formed. H₂ N + Select to Draw 00 Q BnOH H2SO4 H₂O OH- Select to Draw BOC-Ala DCC Select to Draw

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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The image displays a chemical reaction flowchart template with three main interconnected sections, labeled "Select to Draw," indicating the user should input specific chemical structures. 1. **Initial Setup**: - At the top left (first section), a two-directional arrow suggests the interaction between water (H₂O) and hydroxide ions (OH⁻) with unknown compounds. 2. **Reaction Pathways**: - One pathway in the upper section includes the transformation under basic conditions (OH⁻) leading towards the top right section (second section), indicating another intermediate or product yet to be drawn by the user. - Below, an acid (CF₃CO₂H) and a solvent (CH₂Cl₂) are specified, pointing towards the bottom left section (third section). 3. **Flow Dynamics**: - Arrows indicate the flow of reactions or transformations among these sections: - A horizontal arrow shows the reaction direction between the first and second sections. - A vertical arrow points downward from the second section, implying sequential progression. - Another vertical line from the middle down connects to the third section, showing interaction with CF₃CO₂H and CH₂Cl₂. This template allows users to visualize and construct potential reaction pathways by filling in the missing chemical structures.
Transcribed Image Text:The image displays a chemical reaction flowchart template with three main interconnected sections, labeled "Select to Draw," indicating the user should input specific chemical structures. 1. **Initial Setup**: - At the top left (first section), a two-directional arrow suggests the interaction between water (H₂O) and hydroxide ions (OH⁻) with unknown compounds. 2. **Reaction Pathways**: - One pathway in the upper section includes the transformation under basic conditions (OH⁻) leading towards the top right section (second section), indicating another intermediate or product yet to be drawn by the user. - Below, an acid (CF₃CO₂H) and a solvent (CH₂Cl₂) are specified, pointing towards the bottom left section (third section). 3. **Flow Dynamics**: - Arrows indicate the flow of reactions or transformations among these sections: - A horizontal arrow shows the reaction direction between the first and second sections. - A vertical arrow points downward from the second section, implying sequential progression. - Another vertical line from the middle down connects to the third section, showing interaction with CF₃CO₂H and CH₂Cl₂. This template allows users to visualize and construct potential reaction pathways by filling in the missing chemical structures.
**Title: Multi-Step Organic Synthesis Problem** **Objective:** Draw the missing organic structures in the following multi-step synthesis. Show all structures at physiological pH (pH = 7.4). Ignore any inorganic byproducts formed. --- **Reaction Scheme:** 1. **Starting Material:** - A bicyclic compound with an amide group present. (Structure shown on the left) 2. **First Reaction:** - Reagents: Benzyl alcohol (BnOH) and sulfuric acid (H₂SO₄) - Product: To be drawn in the box labeled "Select to Draw." 3. **Second Reaction:** - Reagents: BOC-Ala and DCC - Product: To be drawn in the box labeled "Select to Draw." 4. **Third Reaction:** - Reagents: Water (H₂O) and hydroxide ion (OH⁻) - Product: To be drawn in the box labeled "Select to Draw." 5. **Final Note:** - A compound, CF₃CO₂H, is mentioned at the bottom. --- **Instructions:** - Use the provided boxes to sketch the expected organic structures resulting from each step of the synthesis. - Ensure consistency with conditions at physiological pH (7.4). This exercise is designed to test your understanding of reaction mechanisms and ability to predict the structures of intermediate and final products in organic chemistry synthesis.
Transcribed Image Text:**Title: Multi-Step Organic Synthesis Problem** **Objective:** Draw the missing organic structures in the following multi-step synthesis. Show all structures at physiological pH (pH = 7.4). Ignore any inorganic byproducts formed. --- **Reaction Scheme:** 1. **Starting Material:** - A bicyclic compound with an amide group present. (Structure shown on the left) 2. **First Reaction:** - Reagents: Benzyl alcohol (BnOH) and sulfuric acid (H₂SO₄) - Product: To be drawn in the box labeled "Select to Draw." 3. **Second Reaction:** - Reagents: BOC-Ala and DCC - Product: To be drawn in the box labeled "Select to Draw." 4. **Third Reaction:** - Reagents: Water (H₂O) and hydroxide ion (OH⁻) - Product: To be drawn in the box labeled "Select to Draw." 5. **Final Note:** - A compound, CF₃CO₂H, is mentioned at the bottom. --- **Instructions:** - Use the provided boxes to sketch the expected organic structures resulting from each step of the synthesis. - Ensure consistency with conditions at physiological pH (7.4). This exercise is designed to test your understanding of reaction mechanisms and ability to predict the structures of intermediate and final products in organic chemistry synthesis.
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