Give IUPAC names to the following molecules. CI b. Br CI- Br C. CI Br Draw all the products (alkyl halides) of the following reactions and classify them as primary.
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Can you answer the questions and explain it
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of products.
1.
4.
React the following with (b) NBS, hv, CCI4. Indicate the major product if there are multiple possible.
7.
OH
React the alcohols 7-10 with all reagents (c)-(g). There may be some No Reaction (NR). This may be a
good time to try doing a spider diagram.
(c) HBr
(d) HCI (e) HI (f) SOCI₂, Py (g) PBr3
11.
2.
8.
1. Li
1. Mg
(h) Mg (i) 2. Cul (1) 2. H30+
CI
5.
React alkyl halides 11-13 with all reagents (h)-(l).
1. Li
(k) 2. Cul
3. CH3 Br
ОН
12.
9.
MgBr
(1) 2. MB
1. Mg
Br
3.
-OH
Br
6.
10.
13.
OH"
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CI
a.
b.
b.
b.
C.
d.
Br
CI-
Draw all the products (alkyl halides) of the following reactions and classify them as primary,
secondary, or tertiary
a.
OH
X
.
Br
Br
Complete the following reactions by filling in the missing reagents.
a.
OH
NBS
hv
OH
hv, CC14
Br
NBS
ť
Licu
C.
-MgBr
CI
→
CI
Br
Br"
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