does BPG bind to deoxyhemoglobin only？why BPG does not bind to oxyhemoglobin？what is chemical structure difference between deoxyhemoglobin and oxyhemoglobin？ #nid100-Percent of saturation50-0-No BPG0₂0B₂With BPGBPG also plays a role in supplying a growing fetus with oxygen. The fetus ob-tains oxygen from the mother's bloodstream via the placenta. Fetal hemoglobin(Hb F) has a higher affinity for oxygen than does maternal hemoglobin, allow-ing for efficient transfer of oxygen from the mother to the fetus (Figure 4.29).BPG80 100206040O₂ pressure (po, in torrs)N+Figure 4.28 A comparison of the oxygen-bindingproperties of hemoglobin in the presence and absenceof BPG. Note that the presence of the BPG markedlydecreases the affinity of hemoglobin for oxygen.enistor to subbun 4-5 Quaternary Structure of Proteins@Percent of saturationB₁on 24 ought 100 Fetal hemoglobin50-1621a10+0Figure 27 The binding of BPG todeoxyhemoglobin. Note the electrostaticintentions between the BPG and the protein.(lisation, Irving Geis. Rights owned by HowardHughes Medical Institute. Not to be reproducedwithout permission.)Maternalhemoglobin97O, flows frommaternaloxyhemoglobinto fetaldeoxyhemoglobin18 AAsimenA Ils obbl2AO₂ pressure (po, in torrs)Figure 4.29 A comparison of the oxygen-binding capacityquepof fetal and maternal hemoglobins. Fetal hemoglobin binds bould hyr si ayawless strongly to BPG and, consequently, has a greater affinityfor oxygen than does maternal hemoglobin.

Hemoglobin is a globular protein, ie it is roughly spherical. It is a tetramer of two types of…

Answered: does BPG bind to deoxyhemoglobin…

does BPG bind to deoxyhemoglobin only？why BPG does not bind to oxyhemoglobin？ what is chemical structure difference between deoxyhemoglobin and oxyhemoglobin？

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

does BPG bind to deoxyhemoglobin only？why BPG does not bind to oxyhemoglobin？ what is chemical structure difference between deoxyhemoglobin and oxyhemoglobin？

#nid
100-
Percent of saturation
50-
0-
No BPG
0₂
0
B₂
With BPG
BPG also plays a role in supplying a growing fetus with oxygen. The fetus ob-
tains oxygen from the mother's bloodstream via the placenta. Fetal hemoglobin
(Hb F) has a higher affinity for oxygen than does maternal hemoglobin, allow-
ing for efficient transfer of oxygen from the mother to the fetus (Figure 4.29).
BPG
80 100
20
60
40
O₂ pressure (po, in torrs)
N+
Figure 4.28 A comparison of the oxygen-binding
properties of hemoglobin in the presence and absence
of BPG. Note that the presence of the BPG markedly
decreases the affinity of hemoglobin for oxygen.
enistor to subbun 4-5 Quaternary Structure of Proteins
@
Percent of saturation
B₁
on 24 ought 100 Fetal hemoglobin
50-
1621
a1
0+
0
Figure 27 The binding of BPG to
deoxyhemoglobin. Note the electrostatic
intentions between the BPG and the protein.
(lisation, Irving Geis. Rights owned by Howard
Hughes Medical Institute. Not to be reproduced
without permission.)
Maternal
hemoglobin
97
O, flows from
maternal
oxyhemoglobin
to fetal
deoxyhemoglobin
18 AA
simenA Ils obbl2
A
O₂ pressure (po, in torrs)
Figure 4.29 A comparison of the oxygen-binding capacityque
p
of fetal and maternal hemoglobins. Fetal hemoglobin binds bould hyr si ayaw
less strongly to BPG and, consequently, has a greater affinity
for oxygen than does maternal hemoglobin.

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