DNA intercalator and DNA alkylators are anticancer agents utilized to prevent aggressive cell division. Can you design/propose a small molecule / peptide which can work both as DNA alkylator and DNA intercalator? Rationalize your proposal.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
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DNA intercalator and DNA alkylators are
anticancer agents utilized to prevent
aggressive cell division. Can you
design/propose
a small molecule / peptide
which can work both as DNA alkylator and
DNA intercalator? Rationalize your proposal.
Transcribed Image Text:DNA intercalator and DNA alkylators are anticancer agents utilized to prevent aggressive cell division. Can you design/propose a small molecule / peptide which can work both as DNA alkylator and DNA intercalator? Rationalize your proposal.
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