Disubstituted amides often have lower boiling points than unsubstituted amides. What is the main reason for this observation? Disubstituted amides can form more hydrogen bonds than unsubstituted amides. Disubstituted amides usually have higher molecular weights than unsubstituted amides. Disubstituted amides have less branching than unsubstituted amides. Disubstituted amides have more branching than unsubstituted amides. Disubstituted amides cannot form hydrogen bonds whereas unsubstituted amides can form the hydrogen bonds.

Q: Explain why a 1 ° amine and a 3 ° amine having the same number of carbons are soluble in water to a…

A: Primary and secondary amines have higher boiling points than those of alkanes or ethers of similar…

Q: All primary amines can be utilized to initiate a diazotization process. True or False

A: In diazotization reaction, the nitrous acid reacts with aromatic amines to yield the diazonium salt.

Q: Explain the following giving a reason in each case   Why is an alkylamine more basic than ammonia?…

A: An effective base is the species that donate the electron readily. The electron donating effect of…

Q: What amide(s) will form each of the following amines on treatment with LiAlH4?

A: LiAlH4 is the strong reducing agent. It will reduce the carbonyl group present in amide into CH2…

Q: 6. The reaction between aniline and nitrous acid at low temperature yields A) an N-nitroso amine B)…

A: This question is multiple Questions because it is contains two questions, so for multiple Questions…

Q: Primary and secondary amines exhibit hydrogen bonding; tertiary amines do not. Explain.

A:

Q: 17.56 What amides will form each amine on treatment with LIAIH4? a. oso b.

A:

Q: Which of the following best differentiate the acetanilide from p-nitroacetanilide?…

A:

Q: None

A: carboxylic acids have the -COOH group ,evident in CH₃COOH. Amides feature a -CONH- group,seen in…

Q: What amide(s) can be used to prepare each amine by reduction?

A: a.

Q: Quinapril (trade name Accupril) is a drug used to treat hypertension andcongestive heart failure.…

A: Given compound,

Q: Complete equations for the hydrolysis of the amides  in concentrated aqueous NaOH. Show all products…

A:

Q: Explain which amide (A, B or C) would be mainly found in the hexane layer, if there are all added to…

A: Basic rule of solubility states that like dissolves like that is polar one are mainly stays in polar…

Q: Draw the structure of the following three isomeric amides with chemical formula C,HNO. Amide #1:…

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Q: Given the following compounds Which amine is the least basic? Most basic? Which will not react with…

A: Given amines are :  Which amine is the least basic? Most basic = ? Which will not react with…

Q: Which amines cannot be prepared by a Gabriel synthesis? Explain your choices. NH2 NH2 NH2 а. b. C.…

A: Gabriel's phthalimide synthesis is used for the conversion of primary alkyl halide into primary…

Q: Amines can be protected by different protecting groups as indicated below. Which of the following is…

A: Amines can be protected by various protecting groups. There are various groups like carboxybenzyl…

Q: 'N' N. • HCI N. H3C`CH3

A: •Tripelennamine having various applications because it's metabolites show various properties…

Q: Explain why a secondary amine forms a nitrosamine rather than a diazonium salt when it reacts with…

A:

Q: In the 1880's, Acetanilide, sold under the name Antifebrin, was widely used as a pain reliever and…

A: Here we have to write the mechanism of acid catalyzed hydrolysis of acetanilide and synthesis of…

Q: Paroxetine (Paxil) is an antidepressant that is a member of a family of drugs known as Selective…

A: In the given reaction, usage of SOCl2 is the best reagent to carry out halogenation as in this…

Q: Explain why a secondary amine forms a nitrosamine rather than a diazonium ion when it reacts with…

A: To understand the reaction consider the reaction of a primary amine with nitrosonium ion. The…

Q: Write equations for the hydrolysis of these amides in concentrated aqueous HCl. Show all products as…

A: Cyclic amide is named as lactam.  Lactams are named according to the ring size number. An example…

Q: Show how to convert amines to other functional groups, and devise multistepsyntheses using amines as…

A:

Q: Draw the structure of the following three isomeric amides with chemical formula CgH1¡NO. Amide #1:…

A: Isomers are defined as compounds having the same molecular formula but have a difference in the…

Q: Provide the systematic name for each of the following isomeric amides with the chemical formula CH₁,…

A: E/Z describes alkene stereochemistry. Higher priority groups on the same side = Z (together).…

Q: Which one of the following is a good protecting group for the amine R2NH if it has to protect…

A: Protection group are used to protect amine from attack of acid or base. Though some protection…

Q: Which of the following statements is true?

A: Amines are basic in nature due to the lone pair present on the nitrogen atom that can be donated.

Q: Give a systematic name and a common name (if it has one) for each of the following amines and…

A: An amine is generally a functional group with a nitrogen atom having a lone pair. Amines resemble…

Q: Which of the following statements are true regarding the relative electrophilicity of acetic…

A: The given molecule is acetic anhydride. Draw the structure of this compound.

Q: Draw a picture illustrating a hydrogen bonding interaction between methyl methacrylate and acetone…

A: Hydrogen bonding interaction is defined as hydrogen bonding between hydrogen bond donor and hydrogen…

Q: Draw the structural formula for each amides. - N-Cycloclohexylacetamide - Benzamide

A: Given compounds: - N-Cyclohexyl acetamide - Benzamide

Q: What products are formed when all of the amide and ester bonds are hydrolyzed in each of the…

A: Hydrolysis refers to cleavage of a bond using water. Amide bond is hydrolysed to give an amine and…

Q: Classify the amides in dolastatin, an anticancer compound isolated from the Indian seahare Dolabella…

A: When we talk about the primary, secondary and tertiary the N that is attached to 1 carbon atom is…

Q: Which of the following reducing agents is used in a reductive amination? You may choose more than…

A: An organic conversion is a process of converting one organic chemical to another organic compound…

Q: Explain how the class I carbonyl compound reacts? What will be the product when ethylamine and…

A: Hello. Since your question has multiple parts, we will solve the first part and its three sub-parts…

Q: N. NH2 a b N N. d I Z

A: The basicity of Amine depend upon various factors such as . Delocalization of lone pair effect.…

Q: Explain why a secondary amine forms a nitrosamine rather than a diazonium ion when it reacts with a…

A: Given reaction is:

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.