Directions: This is a manual simulation of COVID-19 RT-PCR test. Determine if the given results of COVID-19 sample are accurate. Analyze the DNA found in each swab sample if it has a matching viral DNA sequence of SARS Cov-2 or the virus that causes COVID-19 using mRNA transcription and tRNA translation. Write CONFIRMED if the sequence of the amino acid shows a positive COVID- 19 result(matches with the amino acid sequence below); write NEGATIVE if the result given does not match with amino acid sequence given below. SARS CoV-2 AA Sequence - Start|Val-Ser-Leu-Gly | His-Pro-Pro | Ser-Ser | Asp-Lys-Gly-Pro | Leu- SeriStop 1. Viral DNA is detected on Probable Case 256789 GTA-TCT-CTT-GGT DNA Repiica ATG AGT-TCA GAC-AAG-GGT-Ccc TAG MANA Strand IRNA Strand AA Sequence 2. Viral DNA is detected on Probable Case @256790 GTT-TOO-CTO-GGT DNA Replica ATG CAT-CCA-CCC AGT-AGT GAT-AAA-GGG-AAG TGA MRNA Strand tRNA Strand AA Sequence
Directions: This is a manual simulation of COVID-19 RT-PCR test. Determine if the given results of COVID-19 sample are accurate. Analyze the DNA found in each swab sample if it has a matching viral DNA sequence of SARS Cov-2 or the virus that causes COVID-19 using mRNA transcription and tRNA translation. Write CONFIRMED if the sequence of the amino acid shows a positive COVID- 19 result(matches with the amino acid sequence below); write NEGATIVE if the result given does not match with amino acid sequence given below. SARS CoV-2 AA Sequence - Start|Val-Ser-Leu-Gly | His-Pro-Pro | Ser-Ser | Asp-Lys-Gly-Pro | Leu- SeriStop 1. Viral DNA is detected on Probable Case 256789 GTA-TCT-CTT-GGT DNA Repiica ATG AGT-TCA GAC-AAG-GGT-Ccc TAG MANA Strand IRNA Strand AA Sequence 2. Viral DNA is detected on Probable Case @256790 GTT-TOO-CTO-GGT DNA Replica ATG CAT-CCA-CCC AGT-AGT GAT-AAA-GGG-AAG TGA MRNA Strand tRNA Strand AA Sequence
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:ACTIVITY 2. COVID-19 RT-PCR TEST
Directions: This is a manual simulation of COVID-19 RT-PCR test. Determine if the given results of
COVID-19 sample are accurate. Analyze the DNA found in each swab sample if it has a matching
viral DNA sequence of SARS CoV-2 or the virus that causes COVID-19 using MRNA transcription
and tRNA translation. Write CONFIRMED if the sequence of the amino acid shows a positive COVID-
19 result(matches with the amino acid sequence below); write NEGATIVE if the result given does
not match with amino acid sequence given below.
SARS CoV-2 AA Sequence - Start Val-Ser-Leu-Gly | His-Pro-Pro | Ser-Ser | Asp-Lys-Gly-Pro | Leu-
SeriStop
1. Viral DNA is detected on Probable Case #256789
ATG
DNA Repilica
GTA-TCT-CTT-GGT
CAC-CCC-CCG
AGT-TCA
GAC-AAG-GGT-CCC
TAG
MRNA Strand
IRNA Strand
AA Sequence
2. Viral DNA is detected on Probable Case #256790
DNA Replica
ATG
GTT-TOG-CTG-GGT
CAT-CCA-Cc
AGT-AGT
GAT-AAA-GGG-AAG
TGA
MRNA Strand
tRNA Strand
AA Sequence
3. Viral DNA is detected on Probable Case #256791
DNA Replica
CAG-CCG-OCC
ATG
GTG-TCA-CTA-GGA
TCC-TCT
GAC-GAC-GGC-CCA
TAA
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MRNA Strand
tRNA Strand
AA Sequence
Expert Solution
Step 1
The synthesis of m RNA is from the template strand of DNA which is complementary to the coding strand of DNA. This process is called transcription. The translation is the synthesis of proteins that is the addition of amino acids and their joining by peptide bonds is called translation.
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