Describe what happens in glutamate excitotoxicity. Define what it is, ane list two conditions that can be manifested. What are the best interventions to treat it.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Describe what happens in glutamate excitotoxicity. Define what it is, ane list two conditions that can be manifested. What are the best interventions to treat it.

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Depending on the timing and extent of ischemia, many mechanisms, such as necrosis, apoptosis, autophagy, necrosis, necroptosis, etc., cause cell death. Due to a severe deficiency in oxygen and glucose, or an absence of both, necrosis primarily develops in the ischemic core. On the other hand, apoptosis occurs in the ischemic penumbra, where some oxygen and glucose levels are still present, keeping cells' functional activity.

 

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