describe the mechanism of ACTION/S of rosuvastatin 2. identify the AIM of rosuvastatin therapy for Mehmet 3. relate rosuvastatin therapy to Mehmet's pathophysiological presentation
Mehmet Yavuz is 62 yo. He presented to the clinic and after having an HbA1c test (result 9%) was diagnosed with type 2 Diabetes mellitus.
His cardiovascular risk was > 15% http://www.cvdcheck.org.au/
His renal health screen showed an eGFR 90 mL/min/1.73m2 with microalbuminuria of 3.5 mg/mmol.
http://www.kidney.org.au/HealthProfessionals/DetectingCKD/tabid/632/Default.aspx
He attended a podiatry appointment which detected decreased dorsalis pedis and posterior tibialis pulses in both legs.
Management of his condition now includes the following:
- Exercise: at least 150 minutes of aerobic and 60 minutes of resistance exercise each week
- Diet: a plan worked out with an accredited dietician based on the Australian Dietary Guidelines (2013).
- Drug use: smoking cessation plan to stop cigarette use; alcohol consumption reduction to 1 - 2 full strength beers every second day
- Weight loss: Mehmet aims to lose 5 kg over the first 6 - 8 weeks after diagnosis
Medications:
- Jardiamet (empagliflozin 5mg, metformin 500 mg), twice daily, with or after food
- ramipril 5 mg, daily
- Rosuzet (rosuvastatin 20mg, ezetimibe 10mg), daily
Ongoing diagnostics:
- HbA1c: every 3 months
- lipid profile: every 3 months
- renal function assessment: annually
- podiatrist assessment: at least once a year
- optometrist assessment: at least once a year
QUESTION:
ONLY DISSCUSS ABOUT rosuvastatin based on each questions below.
1. describe the mechanism of ACTION/S of rosuvastatin
2. identify the AIM of rosuvastatin therapy for Mehmet
3. relate rosuvastatin therapy to Mehmet's pathophysiological presentation
4. refer briefly to any australian GUIDELINES which support the use of rosuvastatin medication
5. identify one RISK or special consideration for Mehmet whilst taking rosuvastatin
6. identify what evidence will demonstrate the EFFECTIVENESS of rosuvastatin therapy
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