Describe the interkinetic nuclear movement

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Describe the interkinetic nuclear movement 

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Interkinetic nuclear movement refers to the process where nucleus moves within the cytoplasm of elongated neuroepithelial progenitor cells and in phase with the cell cycle. Thus, this movement helps in developing neuroepithelia, consisting of the periodic movement of the cell nucleus in phase with cell-cycle progression. This developing neuroepithelia are made of neural progenitor cells, each of which is passing over the thickness of the epithelium from the ventricular surface to laminal side. Cell nucleus take different positions along the apical–basal axis of the tissue, but mitosis takes place closer to the apical side. This nucleus then move to upper regions near the basal side and proceed through S-phase. This nuclear movement is repeated at each cell cycle. This movement is maintained by apical to basal movement during G1-phase and a reverse basal to apical movement during G2-phase.



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