describe how the pyruvate dehydrogenase complex is regulated?

Q: can you explain the catalytic mechanism of pyruvate dehydrogenase (complex)

A: Pyruvate dehydrogenase is a multimeric protein involved in the glycolytic pathway of the cell which…

Q: Explain what will happen to reactions of pyruvate dehydrogenase complex when there is a deficiency…

A: Pyruvate dehydrogenase complex (PDC) is a complex formed by 3 enzymes that converts pyruvate into…

Q: What are the regulatory means that prevent high levels of activity in glycolysis and gluconeogenesis…

A: Glycolysis is the first step of cellular respiration that deals with the breakdown of glucose to…

Q: Identify the enzymes that are considered rate limiting in glycolysis and the citric acid cycle.

A: A metabolic chemical reaction either completes in one step or completes in more than one step in…

Q: Which steps of aerobic metabolism of pyruvate through the citric acid cycle are control points?

A: Cellular respiration can be defined as the series of metabolic reactions that occur in the living…

Q: How is succinate dehydrogenase unique compared with the other enzymes in the citric acid cycle?

A: The citric acid cycle is a catabolic process. It is also known as the TCA cycle or Krebs cycle. It…

Q: ist the inhibitors and activators of the Pyruvate Dehydrogenase Complex observed in most species?

A: Pyruvate dehydrogenase (PDH) complex is a multi-enzyme complex and catalyzes conversion of pyruvate…

Q: [Six/three/one] enzymes that participate in the complete catabolism of glucose through glycolysis…

A: Glycolysis is the breakdown of glucose molecules to yeild energy in the form of ATP and NADH.…

Q: How many molecules of CO2, NADH, and FADH2 are releasedper pyruvate oxidized in the citric acid…

A: Cell is the smallest structural and, functional unit of life. It is simple machinery that houses all…

Q: How does an increase in the NADH/NAD+ratio affect the activity of pyruvate dehydrogenase?

A: The enzyme pyruvate (PDH) dehydrogenase is the major protein complex that helps to connect…

Q: Most defects in pyruvate dehydrogenase complex are due to mutations in ______, so supplements with…

A: Introduction  Pyruvate dehydrogenase is a complex of enzymes that plays a critical role in aerobic…

Q: By the reaction catalyzed by the pyruvate dehydrogenase complex: a) NAD+ is oxidized to become NADH…

A: The glycolytic process results in pyruvate, which is a substantial source of acetyl-CoA for the TCA…

Q: How does an increase in the NADH/NAD1 ratio affect the activity of pyruvate dehydrogenase?

A: Introduction: The citric acid cycle is a series of reactions that yield two carbon dioxide…

Q: Identify the three important products of the oxidative pentose phosphate pathway AND indicate how…

A: The Oxidative Pentose Phosphate pathway is a metabolic pathway alternative to glycolysis for…

Q: How are enzymes in Citric Acid Cycle regulated? What are these enzymes and their inhibitors?

A: Cellular metabolism is the set of all reactions that are involved in producing energy in the body.…

Q: What enzymes from the citric acid cycle that are allosterically regulated by ATP and/or NADH?  What…

A: TCA cycle: - In this cycle, the activated acetate derived from pyruvate undergoes stepwise oxidation…

Q: What effect does a higher ADP/ATP ratio have on isocitrate dehydrogenase activity?

A: Isocitrate dehydrogenase is an enzyme that catalyzes isocitrate's oxidative decarboxylation,…

Q: Of the allosteric enzymes listed below, which are suppressed by NADH? Select all that apply. the…

A: Enzymes catalyse biochemical reactions. Substrate binds to the enzyme's active site and is converted…

Q: How does increasing the ADP/ATP ratio influence isocitrate dehydrogenase activity?

A: A Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate, resulting in…

Q: Pyruvate dehydrogenase can be activated by

A: Introduction Pyruvate dehydrogenase(PDH) is an enzyme complex of three individual enzymes along with…

Q: Which amino acids can be converted to pyruvate by a single enzyme-catalyzed reaction?

A: Pyruvate is a three-carbon compound that is the end product of the glycolysis pathway. Pyruvate is…

Q: What would be the effect of the inhibition on other intermediates in the citric acid cycle?

A: Citric acid cycle occurs in the matrix of mitochondria (cytosol in prokaryotes). The net result of…

Q: Distinguish between catalytic coenzymes and stoichiometric coenzymes in the pyruvate dehydrogenase…

A: The Pyruvate dehydrogenase complex consists of five different coenzymes such as thiamine…

Q: Explain How arsenic affects the pyruvate dehydrogenase reaction

A: Pyruvate dehydrogenase reaction is a reaction in which pyruvate is converted into acetyl-CoA.

Q: Compare the oxidation states of glucose and pyruvate. Explain why glycolysisgenerates NADH.

A: In cells, glucose, a six-carbon sugar, is converted into smaller sugars through a series of…

Q: Describe the movement of energy during acetyl–CoA formationand the citric acid cycle.

A: It takes acetyl CoA start text, C, o, A, end text—produced by the oxidation of pyruvate and…

Q: Which of the following is true about comparing the α-ketoglutarate dehydrogenase complex and the…

A: The Citric Acid Cycle is the one where acetyl CoA acts as the substrate and undergoes a chain of…

Q: Briefly describe the role and location of each cofactor/coenzyme involved in the pyruvate…

A: Pyruvate is the end product of glycolysis. Under aerobic conditions, pyruvate is oxidised into…

Q: How does pyruvate from glycolysis get to the pyruvate dehydrogenase complex?

A: Pyruvate dehydrogenase complex : It is a complex of three enzymes that converts pyruvate into…

Q: Why is it reasonable for excess NADH to negatively regulate the citric acid cycle?

A:

Q: A specialized lysine-linked co-enzyme often participates in the transfer of carbon fragments within…

A: The small non-protein organic molecules which work along with enzymes in various catalytic reactions…