Derive the complete rate equation using the King altman method. Example is shown above the reaction mechanism. All the N terms must be derived. ### Transcription of the Image: Kinetic Reaction Mechanisms#### Mathematical Equations and Derivations:1. **Equation for NFA:** \[ NFA = k_1k_Ak_4k_6(I) + k_1k_3k_4k_6(I)(A)(I) \] \[ + k_5k_6k_3k_4k_{10}(A)(E) + k_4k_6k_6k_{10}(P)(I) \]2. **Expression for \( v_0 \):** \[ v_0 = E_T \left[ \frac{k_1N_Er - k_8(P)N_E}{\sum N_i} \right] \]3. **Relationship showing the chemical equilibrium:** \[ E + A \rightleftharpoons EA \overset{k_3}{\rightleftharpoons} EAB \underset{k_8}{\overset{k_6}{\rightleftharpoons}} EP \rightleftharpoons E + P \]#### Conceptual Notes:- **Derivation Objective:** Derive the complete rate equation \( v_0 = \).- **Inhibition Context:** Competitive inhibition with respect to \( A \).#### Diagrams:- **Chemical Reaction Diagram:** - Shows various rate constants and interactions between substrates and enzymes (represented by \( E \), \( A \), \( I \), \( P \)). - Reactions are indicated with double-headed arrows (e.g., \(\rightleftharpoons\) for equilibrium) and specific reaction rate constants (e.g., \( k_1, k_3, k_4, k_6, k_{10} \)).This transcription provides an overview of kinetic reactions involving enzymes and inhibitors, ideal for educational purposes.

Competitive Inhibition – Competes with substrate for active site. Substrate and inhibitor has…

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Derive the complete rate equation using the King altman method. Example is shown above the reaction mechanism. All the N terms must be derived.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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