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Decide whether each molecule in the table below could be found embedded in the outer surface of a cell membrane. For each molecule that could, decide whether the outside of the cell would lie to the right or left of the molecule as drawn. Note for advanced students: none of these molecules are actually found in cell membranes. Your goal is to use the principles of biochemistry to decide whether they could be, if for example they were synthesized and studied as drug candidates. HO d OH OH molecule OH "NH₂ CH3 CH3 Could be in a membrane? O yes @no O yes O no yes no Ⓒyes Ono Membrane would be to the..? + left + left + left + left right → right → right → right → X S P do Ar V

Decide whether each molecule in the table below could be found embedded in the outer surface of a cell membrane. For each molecule that could, decide whether the outside of the cell would lie to the right or left of the molecule as drawn. Note for advanced students: none of these molecules are actually found in cell membranes. Your goal is to use the principles of biochemistry to decide whether they could be, if for example they were synthesized and studied as drug candidates. HO d OH OH molecule OH "NH₂ CH3 CH3 Could be in a membrane? O yes @no O yes O no yes no Ⓒyes Ono Membrane would be to the..? + left + left + left + left right → right → right → right → X S P do Ar V

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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**Title: Evaluating Molecules for Potential Membrane Embedding** **Introduction:** Decide whether each molecule in the table below could potentially be embedded in the outer surface of a cell membrane. For each molecule that could, determine whether the outside of the cell would lie to the right or left of the molecule as drawn. **Note for Advanced Students:** None of these molecules are actually found in cell membranes. The goal is to apply biochemical principles to decide their potential integration and orientation in a membrane, if synthesized and studied as drug candidates. *** **Molecule Table Analysis:** 1. **First Molecule:** - **Structure:** A complex organic molecule with hydroxyl (OH) groups and an amino group (NH2). - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right 2. **Second Molecule:** - **Structure:** A long hydrocarbon chain with a branched segment. - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right 3. **Third Molecule:** - **Structure:** Includes an ether linkage and a cyclic aliphatic group. - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right 4. **Fourth Molecule:** - **Structure:** Contains a long hydrocarbon chain ending in a fused aromatic ring. - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right **Functionality:** - **Explanation Button:** Provides detailed reasoning and concepts required to make decisions. - **Check Button:** Allows users to verify their selections. © 2023 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility
Transcribed Image Text:**Title: Evaluating Molecules for Potential Membrane Embedding** **Introduction:** Decide whether each molecule in the table below could potentially be embedded in the outer surface of a cell membrane. For each molecule that could, determine whether the outside of the cell would lie to the right or left of the molecule as drawn. **Note for Advanced Students:** None of these molecules are actually found in cell membranes. The goal is to apply biochemical principles to decide their potential integration and orientation in a membrane, if synthesized and studied as drug candidates. *** **Molecule Table Analysis:** 1. **First Molecule:** - **Structure:** A complex organic molecule with hydroxyl (OH) groups and an amino group (NH2). - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right 2. **Second Molecule:** - **Structure:** A long hydrocarbon chain with a branched segment. - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right 3. **Third Molecule:** - **Structure:** Includes an ether linkage and a cyclic aliphatic group. - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right 4. **Fourth Molecule:** - **Structure:** Contains a long hydrocarbon chain ending in a fused aromatic ring. - **Could be in a membrane?** (Options: yes or no) - **Membrane would be to the…?** - Left - Right **Functionality:** - **Explanation Button:** Provides detailed reasoning and concepts required to make decisions. - **Check Button:** Allows users to verify their selections. © 2023 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility
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