Cyclohexylmethanol was synthesized from the hydroboration-oxidation reaction. Draw the starting material. Draw the starting material. Select Draw Rings More Erase C H Br HO 1. BH3, THF 2. NaOH, H20, H2O2
Cyclohexylmethanol was synthesized from the hydroboration-oxidation reaction. Draw the starting material. Draw the starting material. Select Draw Rings More Erase C H Br HO 1. BH3, THF 2. NaOH, H20, H2O2
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:**Cyclohexylmethanol Synthesis via Hydroboration-Oxidation Reaction**
**Objective:**
To illustrate the synthesis of cyclohexylmethanol from its starting material using a hydroboration-oxidation reaction.
**Context:**
Cyclohexylmethanol is synthesized through a two-step reaction process involving hydroboration followed by oxidation.
**Instructions:**
Draw the starting material.
**Reaction Details:**
1. **Reagents and Conditions:**
- Step 1: Use Borane (BH₃) in Tetrahydrofuran (THF) as solvent.
- Step 2: Sodium Hydroxide (NaOH), Water (H₂O), and Hydrogen Peroxide (H₂O₂).
2. **Reaction Sequence:**
- The first step involves the addition of borane (BH₃) to the starting alkene in a solvent (THF).
- The second step entails oxidation with NaOH and H₂O₂ in the presence of water.
**Product:**
The resulting product is cyclohexylmethanol, a cyclohexane ring with a methanol (CH₂OH) group attached.
**Diagram Explanation:**
- The illustration shows the chemical structure of cyclohexylmethanol with the OH group attached to a carbon adjacent to a cyclohexane ring.
- The arrow represents the transformation process from starting material to product, using the stated chemical reactions.
**Interactive Tools:**
- Users can employ drawing tools to recreate the starting material, facilitating learning engagement through visualization.
- Available drawing tools include options to select chemical elements (C, H, Br) and structure sketching tools to modify or draw the chemical structures necessary for the synthesis pathway.
**Endnote:**
Understanding this reaction sequence is crucial for comprehending the method of converting alkenes into alcohols through hydroboration-oxidation, a fundamental reaction in organic chemistry.
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