Answered: Create a diagram that illustrates how…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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Question

Create a diagram that illustrates how the purine nucleotide cycle contributes to energy metabolism
in skeletal muscle. Include glycolysis and the citric acid cycle in your drawing.

Expert Solution

Step 1

In the body, cells use glucose for ATP synthesis. A glucose molecule is degraded into two pyruvate molecules via glycolysis. Pyruvate is converted to acetyl CoA through pyruvate dehydrogenase reaction. Acetyl CoA enters the TCA cycle, which produces NADH, FADH2, which then enters oxidative phosphorylation to produce ATP.
The purine nucleotide cycle occurs to maintain the adenine nucleotide levels and to release ammonia from an amino acid.

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