Considering the following energy profile, complete each of the following three statements: a) The (single step overall reaction / multi-step mechanism) A/ requires less energy be added to the system for the reaction to proceed. b) The (first/second / third) A/ step of the mechanism is likely to be the rate-determining step based on its (equal / higher / lower) A/ activation energy. c) The energy change of the reaction is (dependent on / independent of) A/ the pathway between the overall reactants and overall products. Overall (one step) Mechanism (multi-step) Reaction Coordinate Energy
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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