Consider the fate of pyruvate labeled with 14C in each of the following positions: Carbon 1 (carboxyl), carbon 2, and carbon 3. Predict the fate of each labeled carbon during one turn of the citric acid cycle. Which labeled carbon is the last yield 14CO2? How many turns of the cycle are required to release all the labeled carbon as 14CO2?
Organic Chemistry of Metabolic Pathways
Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.
Glucogenesis
Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general definition for glucogenesis or gluconeogenesis is as follows,
Consider the fate of pyruvate labeled with 14C in each of the following positions: Carbon 1 (carboxyl), carbon 2, and carbon 3. Predict the fate of each labeled carbon during one turn of the citric acid cycle. Which labeled carbon is the last yield 14CO2? How many turns of the cycle are required to release all the labeled carbon as 14CO2?
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