CONCEPT QUESTIONS Predict the Product. Provide the stable organic product(s) for the reactions below 1. 1 eq -NH₂ Å 2. H₂O/ HCI HO CI OH 1. (excess) X NH₂ 2. H₂O NH₂ 1.1 eq -NH₂ å & 2. H₂O/HCI pyridine

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question

2a and 2b

**Concept Questions**

**Predict the Product.** Provide the stable organic product(s) for the reactions below.

1. The top reaction:

   - **Reactants:**
     - Left: Cyclohexane-1,3-dione with a methyl group at one of the dione carbons.
     - Right: Propylamine (1 equivalent).

   - **Steps:**
     - 1. 1 eq. Propylamine (NH₂)
     - 2. H₂O / HCl

2. The second reaction:

   - **Reactants:**
     - Left: Acetyl chloride (ethanoyl chloride).
     - Right: Tetrahydrofuran-2-ol.

   - **Steps:**
     - 1. Pyridine

3. The third reaction:

   - **Reactants:**
     - Left: 2-aminophenol.
     - Right: Diketene (excess).

   - **Steps:**
     - 1. Diketene (excess)
     - 2. H₂O

4. The bottom reaction:

   - **Reactants:**
     - Left: 1,3-benzodioxole-4,5-dione.
     - Right: Piperazine (1 equivalent).

   - **Steps:**
     - 1. 1 eq. Piperazine (NH₂)
     - 2. H₂O / HCl

---

In each of the above reactions, the stable organic products formed will depend on the interaction between the reagents and their functional groups, along with the reaction conditions specified. 

- The first reaction typically results in the formation of an imine due to the reaction of a ketone and amine, followed by hydrolysis in acidic conditions.
- The second reaction is an esterification reaction facilitated by pyridine which may result in the formation of an ester.
- The third reaction involves the formation of a lactam when diketene reacts with 2-aminophenol and water hydrolyzes it.
- The fourth reaction may produce a hydroxamic acid through reaction with piperazine followed by hydrolysis.

Detailed mechanisms and exact product structures would require drawing tools and a step-by-step mechanistic description.
Transcribed Image Text:**Concept Questions** **Predict the Product.** Provide the stable organic product(s) for the reactions below. 1. The top reaction: - **Reactants:** - Left: Cyclohexane-1,3-dione with a methyl group at one of the dione carbons. - Right: Propylamine (1 equivalent). - **Steps:** - 1. 1 eq. Propylamine (NH₂) - 2. H₂O / HCl 2. The second reaction: - **Reactants:** - Left: Acetyl chloride (ethanoyl chloride). - Right: Tetrahydrofuran-2-ol. - **Steps:** - 1. Pyridine 3. The third reaction: - **Reactants:** - Left: 2-aminophenol. - Right: Diketene (excess). - **Steps:** - 1. Diketene (excess) - 2. H₂O 4. The bottom reaction: - **Reactants:** - Left: 1,3-benzodioxole-4,5-dione. - Right: Piperazine (1 equivalent). - **Steps:** - 1. 1 eq. Piperazine (NH₂) - 2. H₂O / HCl --- In each of the above reactions, the stable organic products formed will depend on the interaction between the reagents and their functional groups, along with the reaction conditions specified. - The first reaction typically results in the formation of an imine due to the reaction of a ketone and amine, followed by hydrolysis in acidic conditions. - The second reaction is an esterification reaction facilitated by pyridine which may result in the formation of an ester. - The third reaction involves the formation of a lactam when diketene reacts with 2-aminophenol and water hydrolyzes it. - The fourth reaction may produce a hydroxamic acid through reaction with piperazine followed by hydrolysis. Detailed mechanisms and exact product structures would require drawing tools and a step-by-step mechanistic description.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps with 2 images

Blurred answer
Knowledge Booster
Gravimetric Analysis
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY