Classify each statement as either true or false. True Answer Bank One disadvantage of DNA vaccines is that they don't generate significant immunologic memory. Live, attenuated vaccines are more likely to induce cell-mediated immunity than are killed, inactivated vaccines. A DNA vaccine only induces an immune response to a single epitope. False
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- How do vaccines work in the body? How do they utilize adaptive immune response? Also, kindly give an example (i.e., COVID vaccines).Most vaccines are designed to be preventative or prophylactic. What does this mean?Do vaccines produce active or passive humoral immunity? Explain your answer. Why is passive immunity less satisfactory?
- First word box choice is (replicate, chemical and neutralize). The second word box is (toxoid, adjuvant and antibody). the third box is (Langerhans cells, memory T cells, memory B cells). The fourth box is (passive immunity, short term immunity and long term immunity). The fifth box is (antibody, adjuvant and toxoid)Describe and give one example: artificial active acquired immunity artificial passive acquired immunity natural active acquired immunity natural passive acquired immunityThe antibody surface involved in antigen binding varies depending on the size and nature of the antigen. This surface can be concave or flat, and sometimes, can have extended protrusions. This is accomplished by: Flexibility in the hinge regions of the antibody allowing rotation of the antigen-binding sites Some antibodies using V region framework sequences instead of the CDRs to bind antigen The ability of different CDR sequences to form many structurally distinct shapes and surfaces The ability of the same heavy chain to pair with different light chains The differential usage of κ versus λ light chains, as κ chains form concave
- Which of the following statement(s) about DNA vaccines is(are) NOT true? Check all that apply. A.) DNA vaccines are an example of "ex vivo" vaccination; cells are removed from the body, transfected with DNA expressing the antigen(s) of interest, and then the cells are returned to the body. B.) DNA vaccines can be used to immunize with multiple different antigens. C.) DNA vaccines only stimulate B cell responses. D.) DNA vaccines only stimulate T cell responses. DNA vaccines alone often result in poor immunogenicityTo put an end to the COVID-19 pandemic, vaccines were developed against the virus and people eligible to receive these are encouraged to get vaccinated. How do these vaccines work? * The vaccine will not cause the disease, but will help develop the body’s first line of defense. The vaccine mimics the virus that causes the disease and triggers the creation of antibodies. No answer The presence of the virus in the vaccine will improve the innate immune response of the body. The vaccine causes a mild infection that will trigger the production of antibodies against the virus.Explain sooo briefly, ALL DETAILS. I’ll rate. Thanks.
- The majority of vaccines work by eliciting pathogen-specific antibodies that circulate in our bodies and protect us in the event that we are later exposed to that specific pathogen. For most viruses and bacterial toxins that we are vaccinated against, these pre-existing antibodies are protective because They induce mucus production that helps flush the toxin or virus out of the body They bind to the virus or toxin and carry it to the liver where it can be degraded O They neutralize the virus or toxin, preventing it from attaching to and entering our cells They bind to epithelial cells and induce the production of antimicrobial peptidesHerd immunity means that the entire population (not just those who are vaccinated) are protected from a disease. What is one way that herd immunity protects an unvaccinated person (such as an infant who is too young to be vaccinated or a person who is immunocompromised)?Researchers can make monoclonal antibodies by immunizing a mouse with a molecule (or with a microorganism). The resulting antibody-mediated response produces a set of antibodies that recognize different parts of the molecule. The mouse's B cells are then harvested from its spleen and fused with cancerous B cells from a myeloma cell line. The resulting hybrid myeloma ("hybridoma") cells are cloned: Individual cells are grown in tissue culture as separate cell lines. Each cell line produces and secretes antibodies that recognize one part of the immunizing molecule. These antibodies are called monoclonal antibodies, and they can be purified and used for research or other purposes. Monoclonal antibodies are effective for passive immunization, but only in the immediate term. Antibodies produced by one's own immune system can last up to about six months in the bloodstream, but monoclonals delivered in passive immunization often last for less than a week. Why the difference?