On a scrap piece of paper, draw the curved arrow mechanism for the following reaction. Use your mechanism to predict the majororganic product of the reaction and draw it in the space provided.CI1) NHCH₂OCH 3, pyridine2) EtMgBr, THF3) HCI, H₂O

This is a classic example of Weinreb ketone synthesis using Weinreb amide.

Answered: CI 1) NHCH3OCH 3, pyridine 2) EtMgBr,…

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CI 1) NHCH3OCH 3, pyridine 2) EtMgBr, THF 3) HCI, H₂O

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter13: Substitution

Section: Chapter Questions

Problem 2E

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Mole Concept

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Question

On a scrap piece of paper, draw the curved arrow mechanism for the following reaction. Use your mechanism to predict the major
organic product of the reaction and draw it in the space provided.
CI
1) NHCH₂OCH 3, pyridine
2) EtMgBr, THF
3) HCI, H₂O

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