**Enzyme Reaction Diagram Explanation**This diagram illustrates the process of enzyme-mediated catalysis through distinct stages, including the transition state (TS). The sequence involves a substrate interacting with an enzyme's active site, forming an enzyme-substrate complex, progressing through the transition state, and then leading to the production and release of products.1. **(E + S)** - **Substrate binds at the enzyme active site:** The substrate and enzyme are free at this point, ready to interact.2. **Enzyme-substrate complex:** - The substrate is bound to the active site, forming a temporary complex.3. **Transition State (TS):** - Here, the enzyme-substrate complex undergoes structural changes, which lower the activation energy required for the reaction. This state facilitates the conversion of the substrate into products.4. **Products form in the enzyme active site:** - The substrate is converted into products which are positioned within the active site of the enzyme.5. **Products dissociate from enzyme active site:** - The final products are released from the enzyme, leaving the enzyme free to catalyze another reaction.The active site is specifically designed to fit the substrate, ensuring that the reaction occurs efficiently. The process highlights the enzyme's role in lowering activation energy and speeding up biochemical reactions. ### Reaction Pathway Options1. **Option 1:** - (1) ET - (2) ES - (3) E + P - (4) TS - (5) ligand2. **Option 2:** - (1) ES - (2) EX - (3) EP - (4) E + P - (5) TS3. **Option 3:** - (1) EP - (2) TS - (3) ES - (4) E + P - (5) product4. **Option 4:** - (1) ES - (2) TS - (3) EP - (4) E + P - (5) substrate5. **Option 5:** - (1) E + P - (2) TS - (3) EP - (4) ES - (5) enzymeThese options depict different sequences of reaction pathways, commonly used to describe enzyme-catalyzed reactions involving enzymes (E), substrates (S), products (P), and transition states (TS).

Choose the five correct labels for the figure Enzyme Active site Substrate binds at the enzyme active site (E+S)+ 5 Enzyme-substrate complex 1 2 Products form in the enzyme active site 3 Enzyme Products dissociate from enzyme active site 4

Choose the five correct labels for the figure Enzyme Active site Substrate binds at the enzyme active site (E+S)+ 5 Enzyme-substrate complex 1 2 Products form in the enzyme active site 3 Enzyme Products dissociate from enzyme active site 4

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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