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Chloral hydrate is a hypnotic drug known as the "knockout drops". It is a gem-diol and can be prepared from chloral (an aldehyde) via hydration reaction as follows. он H,0 H,0- Chloral Chloral hydrate i) Write the mechanism for the formation of chloral hydrate in acidic condition. ii) Hydration is reversible. A gem-diol can eliminate water to regenerate its aldehyde. However, with regards to the above schematic diagram, chloral hydrate is more stable compared to chloral. Give an explanation for this stability.

Chloral hydrate is a hypnotic drug known as the "knockout drops". It is a gem-diol and can be prepared from chloral (an aldehyde) via hydration reaction as follows. он H,0 H,0- Chloral Chloral hydrate i) Write the mechanism for the formation of chloral hydrate in acidic condition. ii) Hydration is reversible. A gem-diol can eliminate water to regenerate its aldehyde. However, with regards to the above schematic diagram, chloral hydrate is more stable compared to chloral. Give an explanation for this stability.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Chloral hydrate is a hypnotic drug known as the "knockout drops". It is a gem-diol and can be prepared from chloral (an aldehyde) via hydration reaction as follows. он H,0 H,O Chloral Chloral hydrate i) Write the mechanism for the formation of chloral hydrate in acidic condition. ii) Hydration is reversible. A gem-diol can eliminate water to regenerate its aldehyde. However, with regards to the above schematic diagram, chloral hydrate is more stable compared to chloral. Give an explanation for this stability.
Transcribed Image Text:Chloral hydrate is a hypnotic drug known as the "knockout drops". It is a gem-diol and can be prepared from chloral (an aldehyde) via hydration reaction as follows. он H,0 H,O Chloral Chloral hydrate i) Write the mechanism for the formation of chloral hydrate in acidic condition. ii) Hydration is reversible. A gem-diol can eliminate water to regenerate its aldehyde. However, with regards to the above schematic diagram, chloral hydrate is more stable compared to chloral. Give an explanation for this stability.
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