Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions Nucleophilic Addition Reaction Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively - Reduction (hydride attack: H): NaBH, or LIAIH, (stronger) _H 1) NaBH4 2) HⓇ - Grignard reagents (R-MgX) give alcohols MgBr 1) + - Addition of HCN yields cyanohydrins, RCH(OH)CEN NaCN 2) H₂O* HCN
Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions Nucleophilic Addition Reaction Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively - Reduction (hydride attack: H): NaBH, or LIAIH, (stronger) _H 1) NaBH4 2) HⓇ - Grignard reagents (R-MgX) give alcohols MgBr 1) + - Addition of HCN yields cyanohydrins, RCH(OH)CEN NaCN 2) H₂O* HCN
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ISBN:9781305957404
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Transcribed Image Text:Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions
Nucleophilic Addition Reaction
Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively
- Reduction (hydride attack: H): NaBH, or LIAIH, (stronger)
_H
1) NaBH4
2) HⓇ
- Grignard reagents (R-MgX) give alcohols
MgBr
1)
+
- Addition of HCN yields cyanohydrins, RCH(OH)CEN
NaCN
2) H₂0*
HCN
Expert Solution

Step 1: Given
- Reduction of aldehyde with NaBH4
- Reaction of aldehyde with Grignard reagent
- Addition of HCN to ketone
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