Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions Nucleophilic Addition Reaction Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively - Reduction (hydride attack: H): NaBH, or LIAIH, (stronger) _H 1) NaBH4 2) HⓇ - Grignard reagents (R-MgX) give alcohols MgBr 1) + - Addition of HCN yields cyanohydrins, RCH(OH)CEN NaCN 2) H₂O* HCN
Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions Nucleophilic Addition Reaction Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively - Reduction (hydride attack: H): NaBH, or LIAIH, (stronger) _H 1) NaBH4 2) HⓇ - Grignard reagents (R-MgX) give alcohols MgBr 1) + - Addition of HCN yields cyanohydrins, RCH(OH)CEN NaCN 2) H₂O* HCN
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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![Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions
Nucleophilic Addition Reaction
Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively
- Reduction (hydride attack: H): NaBH, or LIAIH, (stronger)
_H
1) NaBH4
2) HⓇ
- Grignard reagents (R-MgX) give alcohols
MgBr
1)
+
- Addition of HCN yields cyanohydrins, RCH(OH)CEN
NaCN
2) H₂0*
HCN](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ffee5a196-0e10-4c2e-9c7f-7471e7c61611%2Fcde3afef-4d27-40ec-815c-7a7f990761c2%2Fks0441i_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Ch19. Aldehydes and Ketones: Nucleophilic Addition Reactions
Nucleophilic Addition Reaction
Aldehydes and ketones are reduced to yield 1° and 2° alcohols, respectively
- Reduction (hydride attack: H): NaBH, or LIAIH, (stronger)
_H
1) NaBH4
2) HⓇ
- Grignard reagents (R-MgX) give alcohols
MgBr
1)
+
- Addition of HCN yields cyanohydrins, RCH(OH)CEN
NaCN
2) H₂0*
HCN
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Step 1: Given
- Reduction of aldehyde with NaBH4
- Reaction of aldehyde with Grignard reagent
- Addition of HCN to ketone
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