Calcitriol (Vitamin D) rises blood calcium concentration in all these ways except___ increases calcium absorption by the small intestine increases calcium resorption from the skeleton increases calcium reabsorption by the kidneys increases the activity of osteoblasts

Numerous physiological processes that are necessary to attain and maintain homeostasis depends critically on calcium. The stimulation of skeletal muscle contraction uses calcium. Additionally, it controls and stimulates the contraction of the heart muscle. Calcium is also necessary for cellular molecule exocytosis.Blood calcium levels are raised by calcitriol. It is a hormone made of steroids produced from vitamin D3. The skin serves as the starting point for vitamin D3 synthesis, which continues in the liver and kidneys, where calcitriol activation takes place. Calcitriol promotes the absorption of calcium for depositing calcium phosphate in the osteoblasts of bone. So, calcitriol is necessary for the development of bone. However, by generating RANKL and boosting osteoclast activity, calcitriol and PTH work synergistically to promote osteoclast activity for bone reabsorption. As a result, the blood calcium content is not increased by the increased activity of osteoblasts. As a result, Option (4) ought to be chosen.Option (1) should not be chosen. The intestinal absorption of calcium is increased by calcitriol. In the intestinal cells, calcium interacts with a cytosolic receptor to generate a calcitriol-receptor complex, which then produces a calcium-binding protein. This protein enhances the intestine's absorption of calcium. Option (2) should not be chosen. It combines with a cytosolic receptor in intestinal cells to generate a compound called calcitriol, which promotes osteoclastic bone resorption by upregulating RANKL and boosting osteoclast activity. Option (3) should not be chosen. By reducing excretion and promoting reabsorption in the thick ascending limb of Henle's loop and the distal tubule, calcitriol reduces the excretion of calcium through the kidney.Answer: Option (4)

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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Calcitriol (Vitamin D) rises blood calcium concentration in all these ways except___

		increases calcium absorption by the small intestine
		increases calcium resorption from the skeleton
		increases calcium reabsorption by the kidneys
		increases the activity of osteoblasts