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Busulfan is a cell cycle non-specific alkylating antineoplastic agent or simply a chemotherapy drug in use since 1959. Busulfan is far more cytotoxic than two molecules of methyl mesylate (CH3OSO2CH3) because it can crosslink DNA strands. Using 1,2-ethanedithiol as a model compound show the structure of the product formed in the following reaction, where two ends of 1,2-ethanedithiol are linked. CH3 -SH HS Busulfan 1,2-ethanedithiol

Busulfan is a cell cycle non-specific alkylating antineoplastic agent or simply a chemotherapy drug in use since 1959. Busulfan is far more cytotoxic than two molecules of methyl mesylate (CH3OSO2CH3) because it can crosslink DNA strands. Using 1,2-ethanedithiol as a model compound show the structure of the product formed in the following reaction, where two ends of 1,2-ethanedithiol are linked. CH3 -SH HS Busulfan 1,2-ethanedithiol

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Busulfan is a cell cycle non-specific alkylating antineoplastic agent or simply a chemotherapy drug in use since 1959. Busulfan is far more cytotoxic than two molecules of methyl mesylate (CH3OSO2CH3) because it can crosslink DNA strands. Using 1,2-ethanedithiol as a model compound show the structure of the product formed in the following reaction, where two ends of 1,2-ethanedithiol are linked. H;C s-CH3 SH HS Busulfan 1,2-ethanedithiol S. H3C S-0 CH3
Transcribed Image Text:Busulfan is a cell cycle non-specific alkylating antineoplastic agent or simply a chemotherapy drug in use since 1959. Busulfan is far more cytotoxic than two molecules of methyl mesylate (CH3OSO2CH3) because it can crosslink DNA strands. Using 1,2-ethanedithiol as a model compound show the structure of the product formed in the following reaction, where two ends of 1,2-ethanedithiol are linked. H;C s-CH3 SH HS Busulfan 1,2-ethanedithiol S. H3C S-0 CH3
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