Briefly describe a method for the preparation of multilamellar vesicles. Define the term thermotropic phase transition and describe the main transition exhibited by lipid bilayers.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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4.
The interaction of Vitamin D3 with lipid membranes may be studied using different techniques. One
approach is to evaluate its effect on the thermotropic phase transition of dipalmitoyl phosphatidylcholine
(DPPC) multilamellar vesicles using Differential Scanning Calorimetry (DSC).
H
HO
Vitamin D3
(a)
Briefly describe a method for the preparation of multilamellar vesicles.
(b)
Define the term thermotropic phase transition and describe the main transition exhibited by lipid
bilayers.
Transcribed Image Text:4. The interaction of Vitamin D3 with lipid membranes may be studied using different techniques. One approach is to evaluate its effect on the thermotropic phase transition of dipalmitoyl phosphatidylcholine (DPPC) multilamellar vesicles using Differential Scanning Calorimetry (DSC). H HO Vitamin D3 (a) Briefly describe a method for the preparation of multilamellar vesicles. (b) Define the term thermotropic phase transition and describe the main transition exhibited by lipid bilayers.
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