NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCEThyroid Troubles:A Case Study in NegativeFeedback RegulationbyBreanna N. HarrisDepartment of Biological SciencesTexas Tech University, Lubbock, TXPart I-Initial Office VisitYou are six months into a year-long internship at Dr. Mara Siddiqui's endocrinology clinic. So far, you've had a greatexperience with Dr. Siddiqui and you've seen patients with a wide range of endocrine issues. Today, you will shadowDr. Siddiqui as she examines Angela Barber, a patient who was referred by her primary care physician. While waiting,you pull up Angela's information on the computer and you find that she is a 52-year-old African American woman.Except for not feeling like herself over the last three months, she has no health issues.Angela arrives at the clinic and you accompany the nurse to the exam room to ger Angela's vitals. Dr. Siddiqui comesinto the exam room and asks Angela what has becen bothering her. Angela tells the doctor that she has been cold, tired,fatigued, and just not feeling up to her normal activities. She has also gained roughly 20 pounds, even though she hasbeen consciously monitoring her food intake. Angela can't understand what is wrong-she went through menopause ayear ago but she insists that the way she is feeling is not related to that change; she also has not changed anything elseabout her normal routine. Dr. Siddiqui listens to Angela and then examines her ears, eyes, and throat; she also listensto Angela's lungs and heart, and palpates her neck and abdomen. All of Angela's vitals and the outcome of the initialexam are within normal range. Dr. Siddiqui tells Angela that she suspects a thyroid issue and would like to order someblood tests.Angela asks about the thyroid and why it is important. Dr. Siddiqui asks you to help explain this hormone system tothe patient.Questions1. Diagram the hypothalamic-pituitary-thyroid axis. Make sure to include the feedback loops and spell out thehormone names.2. What is the physiological role of thyroid hormones? Does T, or T, play a larger role on the target tissues?Explain.Case copyright held by the National Center for CuE

The hypothalamic- pituitary-thyroid axis or thyroid homeostasis forms a part of the neuroendocrine…

Breanna N. Harris Department of Biological Sciences Texas Tech University, Lubbock, TX Part I-Initial Office Visit You are six months into a year-long internship at Dr. Mara experience with Dr. Siddiqui and you've seen patients withe Dr. Siddiqui as she examines Angela Barber, a patient who you pull up Angela's information on the computer and you Except for not feeling like herself over the last three month Angela arrives at the clinic and you accompany the nurse c into the exam room and asks Angela whar has been bother fatigued, and just not feeling up to her normal activities. been consciously monitoring her food intake. Angela can' year ago bur she insists that the way she is feeling is not re about her normal routine. Dr. Siddiqui listens to Angela to Angela's lungs and heart, and palpates her neck and abe exam are within normal range. Dr. Siddiqui tells Angela t blood tests. Angela asks about the thyroid and why it is important. D the patient.

Breanna N. Harris Department of Biological Sciences Texas Tech University, Lubbock, TX Part I-Initial Office Visit You are six months into a year-long internship at Dr. Mara experience with Dr. Siddiqui and you've seen patients withe Dr. Siddiqui as she examines Angela Barber, a patient who you pull up Angela's information on the computer and you Except for not feeling like herself over the last three month Angela arrives at the clinic and you accompany the nurse c into the exam room and asks Angela whar has been bother fatigued, and just not feeling up to her normal activities. been consciously monitoring her food intake. Angela can' year ago bur she insists that the way she is feeling is not re about her normal routine. Dr. Siddiqui listens to Angela to Angela's lungs and heart, and palpates her neck and abe exam are within normal range. Dr. Siddiqui tells Angela t blood tests. Angela asks about the thyroid and why it is important. D the patient.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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