Reactions of Alkyl and Aryl halides
In organic chemistry, an alkyl halide is formed when an atom of hydrogen is switched by a halogen in a hydrocarbon or aliphatic compound. An aryl halide is formed when an atom of hydrogen is substituted by a halogen atom in an aromatic compound. Metals react with aryl halides and alkyl halides and they also go through nucleophilic substitution reactions and elimination reactions.
Zaitsev's Rule in Organic Chemistry
Alexander Zaitsev (also pronounced as Saytzeff), in 1875, prepared a rule to help predict the result of elimination reactions which stated, "The favored product in dehydrohalogenation reactions is that alkene that has the majority of alkyl groups attached to the double-bonded carbon atoms."
Tosylate
Tosylates are important functional groups in organic chemistry, mainly because of two important properties which they possess:
Alkyl Halides
A functional group is a collection of several atoms or bonds with certain characteristic chemical properties and reactions associated with it. There is a presence of a halogen atom (F, Cl, Br, or I; it represents any halogen atom), as a functional group in alkyl halides. Therefore, it can be said that alkanes that contain a halogen compound are called alkyl halides.
Predict the outcome of the following 4 reactions, if the reaction does not occur write N.R. and explain why, if you expect the reaction to be slow draw the product and write slow.
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**Reactant:**
- A primary alkyl bromide (C-Br bond).
**Reagents and Conditions:**
1. **Methanol (MeOH)** in the presence of **Tetrahydrofuran (THF)** as a solvent, represented by the arrow pointing to the right.
2. A subsequent reaction with an acetate ion **(O=C-O⁻)** and **potassium ion (K⁺)** in the presence of **Acetonitrile (MeCN)** as a solvent, denoted by another arrow.
**Product Structure:**
- The product of this reaction mechanism is typically an ester, resulting from the nucleophilic substitution of the bromine atom by the acetate ion.
**Additional Note:**
- Handwritten text indicating the result as "less than 0" is adjacent to the equation, possibly implying a reduced or minimal yield or another specific reaction condition or characteristic.
The diagram visually indicates the transformation of the primary alkyl bromide via nucleophilic substitution."
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1) MeOH will attack on carbocation and form ether.
2) nucleophile will attack on carbocation and form product.
Unlike charges react with ecah other.
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