Consider the following reaction: (1R, 2S)-2-isopropylcyclohexanol H₂SO4 conc. heat (a) Provide the stepwise mechanism for the reaction and discuss the regiochemistry of the reaction. (b) For the pathway leading to the major product: draw a free energy diagram (reaction progress versus free energy) for the reaction. Be sure to label the Axis, transition state(s), energy of activation for each step, and AH, and show the structures of reactants, products, intermediates, and transition state structures.
Consider the following reaction: (1R, 2S)-2-isopropylcyclohexanol H₂SO4 conc. heat (a) Provide the stepwise mechanism for the reaction and discuss the regiochemistry of the reaction. (b) For the pathway leading to the major product: draw a free energy diagram (reaction progress versus free energy) for the reaction. Be sure to label the Axis, transition state(s), energy of activation for each step, and AH, and show the structures of reactants, products, intermediates, and transition state structures.
Chapter17: Alcohols And Phenols
Section17.SE: Something Extra
Problem 33MP
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