Bob, a 49-year-old house painter, arrives for his appointment with Mary, his dental hygienist, to have his teeth cleaned----the first time in three years. Mary takes a complete health and dental history. She makes note of the fact that Bob smokes approximately two packs of cigarettes a day, occasional cigars at parties, and drinks two or three beers daily after working in the hot sun. He is concerned about the appearance of his lips and teeth. Mary carefully observes his face and lips for any abnormal moles or lesions, noticing that Bob has a deep tan and that the left side of his lower lip is raised, firm, and scaly. The lesion is about 9 mm in diameter. Bob tells her that his lip has had that appearance for about a year. Mary also notes that Bob’s skin is quite wrinkled for one his age. Mary urges Bob to make an appointment with a physician for an examination of the scaly lesion. Bob does so the following week. The physician performs a biopsy on the lesion. Histologic examination of the biopsy confirms that Mark has squamous cell carcinoma. Squamous cell carcinoma is the most common type of oral cancer. Its cause is associated with exposure to the sun, consumption of alcohol, and use of tobacco in all forms. Cells in the stratum spinosum of the epidermis undergo anaplasia, transforming into cancer cells and dividing rapidly. Incidence of metastasis is low if the lesion is removed at an early stage. The other 2 skin cancers are malignant melanoma and basal cell carcinoma. What is the difference between these 2 types of cancers? Which type is the least aggressive (UNlikely to spread to other tissues)? Why are fair-skinned individuals more susceptible to skin cancer?
Bob, a 49-year-old house painter, arrives for his appointment with Mary, his dental hygienist, to have his teeth cleaned----the first time in three years. Mary takes a complete health and dental history. She makes note of the fact that Bob smokes approximately two packs of cigarettes a day, occasional cigars at parties, and drinks two or three beers daily after working in the hot sun. He is concerned about the appearance of his lips and teeth.
Mary carefully observes his face and lips for any abnormal moles or lesions, noticing that Bob has a deep tan and that the left side of his lower lip is raised, firm, and scaly. The lesion is about 9 mm in diameter. Bob tells her that his lip has had that appearance for about a year. Mary also notes that Bob’s skin is quite wrinkled for one his age.
Mary urges Bob to make an appointment with a physician for an examination of the scaly lesion. Bob does so the following week. The physician performs a biopsy on the lesion. Histologic examination of the biopsy confirms that Mark has squamous cell carcinoma.
Squamous cell carcinoma is the most common type of oral cancer. Its cause is associated with exposure to the sun, consumption of alcohol, and use of tobacco in all forms. Cells in the stratum spinosum of the epidermis undergo anaplasia, transforming into cancer cells and dividing rapidly. Incidence of metastasis is low if the lesion is removed at an early stage.
- The other 2 skin cancers are malignant melanoma and basal cell carcinoma. What is the difference between these 2 types of cancers?
- Which type is the least aggressive (UNlikely to spread to other tissues)?
- Why are fair-skinned individuals more susceptible to skin cancer?
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