**Exercise 6: Sex-Linked Traits** Humans and other mammals have two sex chromosomes, X and Y. Females have two X chromosomes (XX) and males have an X and Y chromosome. During meiosis, sex chromosomes behave like other chromosome pairs. In humans, for example, sex chromosomes segregate with the autosome pairs during meiosis. Because females have two X chromosomes, all eggs have a single X chromosome. In males (XY), half of the sperm carry a Y chromosome and half carry an X chromosome. The X and Y chromosomes are not homologous; they do not contain matching genes. Genes found only in the X chromosome are X-linked, and genes found only in the Y chromosome are Y-linked. Together, these are sex-linked genes. Hemophilia is a disease in which the person's blood will not clot. The disease is inherited. If you have the dominant gene H, you have normal blood. If you have the recessive gene h, your blood will not clot. Genes for hemophilia are located on the sex chromosomes. Only the X chromosomes have genes for hemophilia. Thus, a female can be X^HX^H, X^HX^h, X^hX^h. A male can be X^HY or X^hY. **Procedure:** 1. Create a Punnett square for parents who are normal but the mother is a carrier for hemophilia. - Father's genotype: ________ - Mother's genotype: ________ What is the likelihood of the boys being hemophiliacs? ________ 2. Create a Punnett square for parents where the father has hemophilia and the mother is a carrier. - Father's genotype: ________ - Mother's genotype: ________ What is the likelihood of the boys being hemophiliacs? ________ What is the likelihood of the girls being hemophiliacs? ________

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**Exercise 6: Sex-Linked Traits**

Humans and other mammals have two sex chromosomes, X and Y. Females have two X chromosomes (XX) and males have an X and Y chromosome. During meiosis, sex chromosomes behave like other chromosome pairs. In humans, for example, sex chromosomes segregate with the autosome pairs during meiosis. Because females have two X chromosomes, all eggs have a single X chromosome. In males (XY), half of the sperm carry a Y chromosome and half carry an X chromosome. The X and Y chromosomes are not homologous; they do not contain matching genes. Genes found only in the X chromosome are X-linked, and genes found only in the Y chromosome are Y-linked. Together, these are sex-linked genes.

Hemophilia is a disease in which the person's blood will not clot. The disease is inherited. If you have the dominant gene H, you have normal blood. If you have the recessive gene h, your blood will not clot. Genes for hemophilia are located on the sex chromosomes. Only the X chromosomes have genes for hemophilia. Thus, a female can be X^HX^H, X^HX^h, X^hX^h. A male can be X^HY or X^hY.

**Procedure:**

1. Create a Punnett square for parents who are normal but the mother is a carrier for hemophilia.

   - Father's genotype: ________
   - Mother's genotype: ________

   What is the likelihood of the boys being hemophiliacs? ________

2. Create a Punnett square for parents where the father has hemophilia and the mother is a carrier.

   - Father's genotype: ________
   - Mother's genotype: ________

   What is the likelihood of the boys being hemophiliacs? ________
   
   What is the likelihood of the girls being hemophiliacs? ________
Transcribed Image Text:**Exercise 6: Sex-Linked Traits** Humans and other mammals have two sex chromosomes, X and Y. Females have two X chromosomes (XX) and males have an X and Y chromosome. During meiosis, sex chromosomes behave like other chromosome pairs. In humans, for example, sex chromosomes segregate with the autosome pairs during meiosis. Because females have two X chromosomes, all eggs have a single X chromosome. In males (XY), half of the sperm carry a Y chromosome and half carry an X chromosome. The X and Y chromosomes are not homologous; they do not contain matching genes. Genes found only in the X chromosome are X-linked, and genes found only in the Y chromosome are Y-linked. Together, these are sex-linked genes. Hemophilia is a disease in which the person's blood will not clot. The disease is inherited. If you have the dominant gene H, you have normal blood. If you have the recessive gene h, your blood will not clot. Genes for hemophilia are located on the sex chromosomes. Only the X chromosomes have genes for hemophilia. Thus, a female can be X^HX^H, X^HX^h, X^hX^h. A male can be X^HY or X^hY. **Procedure:** 1. Create a Punnett square for parents who are normal but the mother is a carrier for hemophilia. - Father's genotype: ________ - Mother's genotype: ________ What is the likelihood of the boys being hemophiliacs? ________ 2. Create a Punnett square for parents where the father has hemophilia and the mother is a carrier. - Father's genotype: ________ - Mother's genotype: ________ What is the likelihood of the boys being hemophiliacs? ________ What is the likelihood of the girls being hemophiliacs? ________
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